Table 1 The frequency and mutations confer resistance to fluoroquinolones
From: Fluoroquinolone resistance and mutational profile of gyrA in pulmonary MDR tuberculosis patients
gyrA Mutation probe | Missing wild type probe | Phenotypic Susceptibility | Mutation | Frequency (n = 102) |
|---|---|---|---|---|
gyr A MUT1 | gyr A WT2 | Resistant | A90V | 25 |
gyr A MUT2 | gyr A WT2 gyr A WT3 | Resistant | S91P | 7 |
gyr A MUT3A | gyr A WT3 | Resistant | D94A | 7 |
gyr A MUT3B | gyr A WT3 | Resistant | D94N/Y | 9 |
gyr A MUT3C | gyr A WT3 | Resistant | D94G | 45 |
None | any one wild type probe | Resistant | A90V D94A D94G | 9 |