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Table 1 Characteristics of patients with interstitial lung diseases (n = 111)

From: Determinants of cough-related quality of life in interstitial lung diseases

Measured variable

 

Age (years)

67.0 (61.0–73.0)

Gender (male)

68 (61.3%)

BMI (kg/m2)

28.1 (26.4–31.1)

Current smoker

13 (11.7%)

Ever smoker

67 (60.4%)

FVC (% predicted)

80.0 (72.0–89.0)

FEV1 (% predicted)

83.0 (73.0–91.0)

DLCO (% predicted) (n = 110)

63.0 (51.4–73.0)

BAL total cell count (n = 83)

98.0 (66.0–160.0)

LCQ total score (n = 110)

16.8 (13.3–18.7)

SGRQ total score (n = 99)

31.4 (16.4–44.0)

Radiological findings

 

 Ground-glass opacity*

3.0 (0.5–6.0)

 Honeycombing*

0.0 (0.0–1.0)

 Reticulation*

9.5 (7.0–11.0)

 Traction bronchiectasis*

0 (0–0.5)

 Emphysema*

3.0 (1.5–5.0)

Precense of histological findings

 

 Fibroblast foci

84 (75.7%)

 Granulomas

8 (7.2%)

 Giant cells

13 (11.7%)

 Fibrosis

105 (94.6%)

 Honeycombing

31 (27.9%)

Diagnoses of multidisciplinary discussion

 

 Idiopathic pulmonary fibrosis

70 (63.1%)

 Non-specific interstitial pneumonia

14 (12.6%)

 Hypersensitivity pneumonitis

11 (9.9%)

 Sarcoidosis

3 (2.7%)

 CTD-ILD

1

 Asbestosis

1

 RB-ILD

1

 COP

1

 Unclassified fibrosis

7 (6.3%)

 Other

2

Patient reported chronic cough comorbidities

 

 Asthma

17 (15.3%)

 GERD

11 (9.9%)

 Chronic rhinosinusitis

1

ACE inhibitor use (n = 110)

14 (12.7%)

ILD-GAP index (n = 110)

 

 0–1

37 (33.6%)

 2–3

58 (52.7%)

 4–5

15 (13.6%)

 >5

0

  1. Values are given as medians with interquartile ranges
  2. BMI, body mass index, FVC, forced vital capacity, FEV1, forced expiratory volume in 1 s, DLCO, diffusion capacity for carbon monoxide, LCQ, The Leicester Cough Questionnaire, SGRQ, The St George’s Respiratory Questionnaire, CTD-ILD, connective tissue disease associated interstitial lung disease, RB-ILD, respiratory bronchiolitis interstitial lung disease, COP, cryptogenic organizing pneumonia, GERD, gastro-esophageal reflux disease, ACE, angiotensin converting enzyme, ILD-GAP index, interstitial lung disease Gender-Age -Physiology index, other: eosinophilic pneumonia, breast cancer, *Interobserver mean score
  3. Other: eosinophilic pneumonia, breast cancer, *Interobserver mean score