Table 1 Baseline characteristics of COPD patients classified according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria

Age, y

74 (6) [75 (70; 78)]

75 (5)

73 (6) [74 (70; 78)]

0.2253

Sex, male/female (n)

112/10

47/4

65/6

0.9040

BMI, kg ⋅ m^− 2

21.5 (3.3)

22.2 (3.1)

21.0 (3.4)

0.0322

Pulmonary function test

FEV₁, L

1.27 (0.58) [1.09 (0.86; 1.58)]

1.81 (0.52) [1.71 (1.49; 2.14)]

0.88 (0.19)

< 0.0001

%FEV₁, % predicted

50.8 (22.4) [45.6 (35.2; 63.7)]

72.0 (18.0) [67.9 (57.6; 82.6)]

35.6 (8.4)

< 0.0001

FEV₁/FVC, %

42.2 (12.2) [40.6 (31.9;49.3)]

51.8 (10.0) [50.0 (43.8; 60.3)]

35.3 (8.2) [32.9 (29.9; 40.0)]

< 0.0001

VC, L

3.05 (0.77)

3.50 (0.68)

2.72 (0.65)

< 0.0001

%VC, %

99.0 (23.1)

113.8 (122.1)

88.5 (20.6)

< 0.0001

IC, L

1.96 (0.52)

2.27 (0.48)

1.73 (0.43)

< 0.0001

Medications (n)

LAMA

102

37

65

0.0052

LABA

92

31

61

0.0015

ICS

64

21

43

0.0344

Triple inhalation therapy

45

10

35

0.0008