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Table 3 Square of the correlation coefficient of parameters related to OUES in COPD patients (n = 122)

From: Gas exchange efficiency slopes to assess exercise tolerance in chronic obstructive pulmonary disease

 

All COPD patients

GOLD I-II (n = 51)

GOLD III-IV (n = 71)

Peak incremental exercise parameters

Dyspnoea, Borg scale

0.02

0.00

0.03

\(\rm{\dot V}\)O2, mL ⋅ min−1 ⋅ kg

0.35

0.60

0.19

\(\rm{\dot V}\)E, L ⋅ min−1

0.27

0.25

0.26

VT, mL

0.27

0.30

0.19

fR, breaths ⋅ min− 1

0.01

0.01

0.00

TI/Ttot

0.03

0.01

0.00

\(\rm{\dot V}\)E/\(\rm{\dot V}\)CO2

0.26

0.31

0.14

HR, beats ⋅ min− 1

0.05

0.09

0.01

O2 pulse, mL ⋅ beats− 1

0.47

0.66

0.35

ΔFO2, %

0.21

0.33

0.17

During exercise

   

ΔFO2 max., %

0.18

0.34

0.07

\(\rm{\dot V}\)E−\(\rm{\dot V}\)CO2 slope

0.25

0.29

0.20

\(\rm{\dot V}\)E/\(\rm{\dot V}\)CO2 nadir

0.22

0.28

0.08

AT (\(\rm{\dot V}\)O2), mL ⋅ min−1

0.39

0.46

0.33

Pulmonary function and others

FEV1, L

0.16

0.19

0.12

VC, L

0.19

0.08

0.07

FVC, L

0.18

0.07

0.14

IC, L

0.17

0.16

0.10

Age, y

0.00

0.00

0.02

BMI, kg ⋅ m− 2

0.14

0.13

0.15

  1. AT: anaerobic threshold; BMI: body mass index; FEV1: forced expiratory volume in one second; FVC: forced vital capacity; ΔFO2: difference between inspired mean oxygen concentration and expired mean oxygen concentration; ΔFO2 max.: the highest ΔFO2 value during exercise; fR: breathing frequency; HR: heart rate; IC: inspiratory capacity; O2 pulse:  \(\rm{\dot V}\)O2/HR; OUES: oxygen uptake efficiency slope (see the Methods for details); TI/Ttot: inspiratory duty cycle; VC: vital capacity; \(\rm{\dot V}\)CO2: carbon dioxide output; \(\rm{\dot V}\)E: minute ventilation; \(\rm{\dot V}\)E/\(\rm{\dot V}\)CO2-nadir: the lowest value during exercise (see the Methods for details); and \(\rm{\dot V}\)E−\(\rm{\dot V}\)CO2-slope: the slope was determined by linear regression analysis of \(\rm{\dot V}\)E to \(\rm{\dot V}\)CO2 obtained during exercise (see the Methods for details); \(\rm{\dot V}\)O2: oxygen uptake; VT: tidal volume