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Table 5 Square of the correlation coefficient of parameters related to \(\rm{\dot V}\)E-\(\rm{\dot V}\)co2 slope in COPD patients (n = 122)

From: Gas exchange efficiency slopes to assess exercise tolerance in chronic obstructive pulmonary disease

 

All COPD patients

GOLD I-II (n = 51)

GOLD III-IV (n = 71)

Peak incremental exercise parameters

Dyspnoea, Borg scale

0.00

0.03

0.00

\(\rm{\dot V}\)O2, mL ⋅ min−1 ⋅ kg

0.15

0.34

0.14

\(\rm{\dot V}\)E, L ⋅ min−1

0.00

0.00

0.00

VT, mL

0.04

0.07

0.06

fR, breaths ⋅ min− 1

0.05

0.04

0.06

TI/Ttot

0.00

0.02

0.00

\(\rm{\dot V}\)E/\(\rm{\dot V}\)O2

0.57

0.55

0.60

HR, beats ⋅ min− 1

0.13

0.23

0.11

O2 pulse, mL ⋅ beats− 1

0.08

0.13

0.06

ΔFO2, %

0.61

0.57

0.63

During exercise

   

ΔFO2 max., %

0.55

0.69

0.45

\(\rm{\dot V}\)E/\(\rm{\dot V}\)CO2 nadir

0.61

0.81

0.54

AT (\(\rm{\dot V}\)O2), mL ⋅ min−1

0.07

0.14

0.09

Pulmonary function and others

FEV1, L

0.00

0.04

0.00

IC, L

0.00

0.01

0.00

Age, y

0.00

0.00

0.01

BMI, kg ⋅ m− 2

0.02

0.00

0.04

  1. AT: anaerobic threshold; BMI: body mass index; FEV1: forced expiratory volume in one second; ΔFO2: difference between inspired mean oxygen concentration and expired mean oxygen concentration; ΔFO2 max.: the highest ΔFO2 value during exercise; fR: breathing frequency; HR: heart rate; IC: inspiratory capacity; O2 pulse: \(\rm{\dot V}\)O2/HR; TI/Ttot: inspiratory duty cycle; \(\rm{\dot V}\)CO2: carbon dioxide output; \(\rm{\dot V}\)E: minute ventilation; \(\rm{\dot V}\)E/\(\rm{\dot V}\)CO2-nadir: the lowest value during exercise (see the Methods for details); \(\rm{\dot V}\)E-\(\rm{\dot V}\)CO2-slope: the slope was determined by linear regression analysis of \(\rm{\dot V}\)E to \(\rm{\dot V}\)CO2 obtained during exercise (see the Methods for details); \(\rm{\dot V}\)O2: oxygen uptake; VT: tidal volume