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Table 1 Baseline characteristics of participants, according to pulmonary function categories at registration

From: Update of prognosis and characteristics of chronic obstructive pulmonary disease in a real-world setting: a 5-year follow-up analysis of a multi-institutional registry

 

FEV1/FVC < 70% (AFL)

 

FEV1/FVC ≥ 70%

 

Total

mild and moderate

(N = 197)

severe

(N = 112)

very severe

(N = 65)

Dunnett test*

(N = 53)

P-value†

 

Age (year.), median (IQR)

72 (67–76)

73 (67–78)

71 (65–75)

0.338/0.165

71 (65–78)

0.849

72 (66–77)

Sex, n (%)

       

 Male

173 (87.8)

94 (83.9)

59 (90.8)

0.536/0.778

46 (86.8)

0.841

372 (87.1)

 Female

24 (12.2)

18 (16.1)

6 (9.2)

 

7 (13.2)

 

55 (12.9)

BMI(kg/m2),

median (IQR)

22.4

(20.0-24.4)

22.1

(19.7–24.0)

19.6

(17.1–22.2) §

0.399/

< 0.001

21.7

(17.8–24.2)

0.052

21.9

(19.2–24.1)

Smoking

(pack-years), median (IQR) ‡

48.0

(30.0–80.0)

50.0

(40.0-72.5)

57.5

(40.0–80.0)

0.985/0.105

48.0

(31.0–80.0)

0.589

50

(36.5–70)

 Never, n (%)

4 (2.0)

2 (1.8)

2 (3.1)

0.419/0.616

3 (5.7)

0.174

11 (2.6)

 Former, n (%)

138 (70.1)

86 (76.8)

48 (73.8)

 

39 (73.6)

 

72.8 (72.8)

 Current, n (%)

55 (27.9)

24 (21.4)

15 (23.1)

 

11 (20.8)

 

24.5 (24.6)

Past history of

Bronchial asthma

27 (13.7)

28 (25.0) §

11 (16.9)

0.020/0.793

5 (9.4)

0.409

71 (16.6)

Comorbidity, n (%)

       

 Diabetes

27 (13.7)

12 (10.7)

10 (15.4)

0.693/0.923

7 (13.2)

0.925

56 (13.1)

 Dyslipidaemia

33 (16.8)

14 (12.5)

5 (7.7)

0.498/0.127

9 (17.0)

0.968

61 (14.3)

 Hypertension

81 (41.1)

45 (40.2)

25 (38.5)

0.982/0.909

28 (52.8)

0.127

179 (41.9)

 Heart disease

35 (17.8)

18 (16.1)

6 (9.2)

0.902/0.189

11 (20.8)

0.618

70 (16.4)

 GERD

13 (6.6)

9 (8.0)

6 (9.2)

0.860/0.726

4 (7.5)

0.808

32 (7.5)

  1. FVC, Forced vital capacity; FEV1, Forced expiratory volume in one second; IQR, Interquartile range; BMI, Body mass index; GERD, Gastroesophageal reflux disease
  2. *: Reference: mild and moderate AFL
  3. †: Chi-square test for nominal scale variables, Wilcoxon rank sum test for continuous variables
  4. ‡: Numbers of patients (mild and moderate AFL, severe AFL, very severe AFL, and FEV1/FVC ≥ 70%, respectively) were as follows: Smoking (N = 196, 110, 64, 53)
  5. §: P < 0.05 with Dunnett’s test, Chi-square, or Wilcoxon rank sum test
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BMC Pulmonary Medicine

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