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Table 2 Baseline symptom and performance status according to pulmonary function categories at registration

From: Update of prognosis and characteristics of chronic obstructive pulmonary disease in a real-world setting: a 5-year follow-up analysis of a multi-institutional registry

 

FEV1/FVC < 70%

 

FEV1/FVC

≥ 70%

 

mild and moderate

(n = 197)

severe

(n = 112)

very severe

(n = 65)

Dunnett test*

(n = 53)

P-value†

mMRC score, n (%) ‡

 

§

§

< 0.001/

< 0.001

 

0.686

 0

22 (15.1)

6 (5.8)

1 (1.8)

 

6 (14.3)

 

 1

71 (48.6)

32 (31.1)

13 (22.8)

 

21 (50.0)

 

 2

38 (26.0)

36 (35.0)

12 (21.1)

 

6 (14.3)

 

 3

13 (8.9)

18 (17.5)

20 (35.1)

 

9 (21.4)

 

 4

2 (1.4)

11 (10.7)

11 (19.3)

 

0 (0.0)

 

Symptom, n (%)

      

 Cough

92 (46.7)

59 (52.7)

39 (60.0)

0.516/0.119

34 (64.2)

0.024

 Sputum

83 (42.1)

47 (42.0)

39 (60.0) §

0.999/0.023

28 (52.8)

0.164

 Body weight loss

5 (2.5)

9 (8.0)

18 (27.7) §

0.150/<0.001

4 (7.5)

0.098

 Wheeze

11 (5.6)

8 (7.1)

9 (13.8)

0.846/0.054

2 (3.8)

1.000

 Clubbed fingers

20 (10.2)

11 (9.8)

4 (6.2)

0.993/0.552

3 (5.7)

0.427

PS, n (%)

 

§

§

< 0.001/

< 0.001

 

0.316

 0

90 (45.7)

24 (21.4)

13 (20.0)

 

22 (41.5)

 

 1

96 (48.7)

68 (60.7)

28 (43.1)

 

24 (45.3)

 

 2

10 (5.1)

15 (13.4)

16 (24.6)

 

7 (13.2)

 

 3

1 (0.5)

5 (4.5)

7 (10.8)

 

0 (0.0)

 

 4

0 (0.0)

0 (0.0)

1 (1.5)

 

0 (0.0)

 
  1. FVC, Forced vital capacity; FEV1, Forced expiratory volume in one second; IQR, Interquartile range; mMRC, Modified Medical Research Council; PS, Performance Status
  2. *: Reference: mild and moderate AFL group
  3. †: Chi-square test for nominal scale variables, Wilcoxon rank sum test for ordered categorical variables
  4. ‡: Numbers of patients (mild and moderate AFL, severe AFL, very severe AFL, and FEV1/FVC ≥ 70%, respectively) were as follows: mMRC (N = 146, 103, 57, 42)
  5. §: P < 0.05 with Dunnett’s test, Chi-square or Wilcoxon rank sum test
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BMC Pulmonary Medicine

ISSN: 1471-2466

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