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Table 1 Characteristics of the patients

From: Transbronchial lung cryobiopsy for interstitial lung disease: early experience, learning curve, and the impact of sedation on complication rates at a single centre in Japan

Variable

n = 119 (100%)

Demographics

Ā 

Age (years)

68.6 ± 9.0

Sex, male

65 (54.6)

BMI (kg/m2)

23.4 ± 4.1

Never smoker

54 (45.4)

Pulmonary Function Tests

Ā 

FVCĀ %predicted (%)

84.3 ± 22.1

FEV1/FVC (%)

79.6 ± 15.2

FEV1%predicted (%)

91.0 ± 20.4

DLCO %predicted (%)

76.2 ± 20.7

Procedural Details

Ā 

Procedural time (min)

38.5 ± 8.6

Fentanyl (µg)

92.4 ± 14.0

Fentanyl (µg/kg/h)

2.58 ± 0.88

Midazolam (mg)

11.8 ± 4.9

Midazolam (mg/kg/h)

0.32 ± 0.14

Number of biopsies

2.3 ± 0.9

Number of biopsies per 30Ā min

1.9 ± 0.9

Biopsy from upper lobes

38 (31.9)

Complications

Ā 

Pneumothorax small

1 (0.8)

large

1 (0.8)

Bleeding mild

82 (68.9)

moderate

26 (21.8)

severe

5 (4.2)

Significant bleeding

31 (26.1)

Respiratory tract infection

3 (2.5)

90-day mortality

0 (0.0)

Histopathological Findings

Ā 

Alveolar tissue obtained

116 (97.5)

Pathological diagnosis achieved

97 (81.5)

  1. Data are presented as mean ± SD or n (%). BMI, body mass index; DLCO, diffusing capacity of the lung for carbon monoxide; FEV1, forced expiratory volume in 1Ā s; FVC, forced vital capacity