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Table 3 Predictors of significant bleeding

From: Transbronchial lung cryobiopsy for interstitial lung disease: early experience, learning curve, and the impact of sedation on complication rates at a single centre in Japan

Variable

Univariable Analysis

Multivariable Analysis

OR (95% CI)

P-values

OR (95% CI)

P-values

Age

0.98 (0.94–1.03)

0.412

Ā Ā 

Male

2.56 (1.06–6.17)

0.037

2.12 (0.85–5.28)

0.106

Never smoker

0.48 (0.20–1.13)

0.091

Ā Ā 

BMI (kg/m2)

1.08 (0.97–1.19)

0.151

Ā Ā 

FVC %predicted (%)

1.01 (0.99–1.03)

0.440

Ā Ā 

FEV1/FVC (%)

1.00 (0.97–1.02)

0.806

Ā Ā 

FEV1%predicted (%)

1.00 (0.98–1.02)

0.946

Ā Ā 

DLCO %predicted (%)

1.02(0.99–1.05)

0.059

Ā Ā 

Number of biopsies

0.91 (0.56–1.47)

0.687

Ā Ā 

Biopsy from upper lobes

1.02 (0.43–2.45)

0.964

Ā Ā 

Fentanyl (µg/kg/h)

0.46 (0.24–0.87)

0.016

0.51 (0.27–0.97)

0.041

Midazolam (mg/kg/h)

9.65 (0.57–165.0)

0.117

Ā Ā 

UIP in histopathology

1.28 (0.41–4.02)

0.667

Ā Ā 

Consolidation phase

1.58 (0.69–3.66)

0.281

Ā Ā 
  1. BMI, body mass index; CI, confidence interval, DLCO, diffusing capacity of the lung for carbon monoxide; FEV1, forced expiratory volume in 1Ā s; FVC, forced vital capacity, OR, odds ratio