The diagnosis value of dual-energy computed tomography (DECT) multi-parameter imaging in lung adenocarcinoma and squamous cell carcinoma

Table 4 Performance indicators of arterial and venous phase DECT parameters and their combined predictive classification

Parameter	AUC	Sensitivity (%)	Specificity (%)	Threshold	95% CI
AP
Zeff	0.70	0.861	0.514	8.525	0.577 ~ 0.823
WC(mg/cm³)	0.65	0.639	0.657	1026.305	0.517 ~ 0.78
IC(mg/cm³)	0.70	0.806	0.571	14.475	0.565 ~ 0.815
NIC(mg/cm³)	0.64	0.778	0.514	0.162	0.506 ~ 0.766
K	0.68	0.750	0.571	1.698	0.549 ~ 0.802
VP
Zeff	0.70	0.861	0.514	8.525	0.577 ~ 0.823
WC(mg/cm³)	0.65	0.639	0.657	1026.305	0.517 ~ 0.780
IC(mg/cm³)	0.69	0.806	0.571	14.475	0.565 ~ 0.815
NIC(mg/cm³)	0.64	0.778	0.514	0.162	0.506 ~ 0.766
K	0.68	0.75	0.571	1.698	0.549 ~ 0.802
Tumor size	0.73	0.694	0.743	3.95	0.605 ~ 0.853
Combined diagnosis	0.83	0.639	0.943	0.60	0.736 ~ 0.926

*P < 0.05. AC: adenocarcinoma; SC: Squamous cell carcinoma; AP: Arterial phase; VP: venous phase. WC: water concentration, IC: iodine concentration, NIC: normalized iodine concentration, Zeff: Z effective; K: slope of the curve

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