Variables | Univariate model | Multivariate model |
---|
HR (95%CI) | P | HR (95%CI) | P |
---|
Acetaminophen use |
No | Ref | | Ref | |
Yes | 0.52 (0.45–0.60) | < 0.001 | 0.67 (0.57–0.78) | < 0.001 |
After PSM |
Acetaminophen use |
No | Ref | | Ref | |
Yes | 0.75 (0.62–0.90) | 0.002 | 0.70 (0.58–0.84) | < 0.001 |
- Univariate model: no adjustment for covariates
- Multivariate model: adjusted race/ethnicity, marital status, temperature, positive end-expiratory pressure, vasopressor, propofol, midazolam, dexmedetomidine, intensive care unit type, Simplified Acute Physiology Score II, Glasgow Coma Score, platelet, red cell distribution width, total bilirubin, lactate, bicarbonate, blood urea nitrogen, and international normalized ratio
- After PSM: Multivariate model adjusted race/ethnicity, marital status, temperature, weight, positive end-expiratory pressure, prothrombin time, vasopressor, propofol, midazolam, dexmedetomidine, intensive care unit type, Simplified Acute Physiology Score II, Glasgow Coma Score, lactate, bicarbonate, and blood urea nitrogen
- PSM propensity score matching, HR hazard ratio, CI confidence interval