Skip to main content

Table 2 Association between acetaminophen use and in-hospital mortality

From: Effects of acetaminophen use on mortality of patients with acute respiratory distress syndrome: secondary data mining based on the MIMIC-IV database

Variables

Univariate model

Multivariate model

HR (95%CI)

P

HR (95%CI)

P

Acetaminophen use

 No

Ref

 

Ref

 

 Yes

0.52 (0.45–0.60)

 < 0.001

0.67 (0.57–0.78)

 < 0.001

After PSM

Acetaminophen use

No

Ref

 

Ref

 

Yes

0.75 (0.62–0.90)

0.002

0.70 (0.58–0.84)

 < 0.001

  1. Univariate model: no adjustment for covariates
  2. Multivariate model: adjusted race/ethnicity, marital status, temperature, positive end-expiratory pressure, vasopressor, propofol, midazolam, dexmedetomidine, intensive care unit type, Simplified Acute Physiology Score II, Glasgow Coma Score, platelet, red cell distribution width, total bilirubin, lactate, bicarbonate, blood urea nitrogen, and international normalized ratio
  3. After PSM: Multivariate model adjusted race/ethnicity, marital status, temperature, weight, positive end-expiratory pressure, prothrombin time, vasopressor, propofol, midazolam, dexmedetomidine, intensive care unit type, Simplified Acute Physiology Score II, Glasgow Coma Score, lactate, bicarbonate, and blood urea nitrogen
  4. PSM propensity score matching, HR hazard ratio, CI confidence interval