Table 1 Respiratory mechanics parameters of the model with two symmetrical compartments, for the 4 profiles and the 2 clinical situations
From: Modeling ventilation of patients with interstitial lung disease at rest and exercise: a bench study
control | mild ILD | moderate ILD | severe ILD | |||||
|---|---|---|---|---|---|---|---|---|
rest | exercise | rest | exercise | rest | exercise | rest | exercise | |
TV (mL) | 673 ± 0 | 1937 ± 0 | 650 ± 0 | 1070 ± 0 | 576 ± 0 | 1126 ± 0 | 546 ± 0 | 835 ± 0 |
EELV (mL) | 2148 ± 0 | 2827 ± 0 | 1488 ± 0 | 3539 ± 0 | 1255 ± 0 | 1863 ± 0 | 1135 ± 0 | 855 ± 0 |
VE (L/min) | 10.1 ± 0 | 62.0 ± 0 | 13.7 ± 0 | 42.8 ± 0 | 12.7 ± 0 | 45.0 ± 0 | 13.7 ± 0 | 33.4 ± 0 |
∆P (cmH2O) | 5.3 ± 0 | 27.8 ± 0 | 6.8 ± 0 | 18.4 ± 0 | 6.9 ± 0 | 20.3 ± 0 | 8.8 ± 0 | 22.5 ± 0 |
∆Ptp (cmH2O) | 3.4 ± 0 | 17.8 ± 0 | 4.3 ± 0 | 7.7 ± 0 | 5.7 ± 0 | 12.8 ± 0 | 10.9 ± 0 | 26.2 ± 0 |
PEEP tot (cmH2O) | 1.0 ± 0 | 8.8 ± 0 | 1.4 ± 0 | 6.8 ± 0 | 0.9 ± 0 | 5.8 ± 0 | 0.4 ± 0 | 2.7 ± 0 |
Strain | 0.31 | 1.89 | 0.44 | 1.05 | 0.46 | 1.26 | 0.48 | 1.22 |
MP (J/min) | 4.3 | 161.2 | 7.3 | 60.8 | 8.3 | 81.9 | 15.2 | 94.6 |
WOB (J/L) | 0.53 ± 0 | 2.72 ± 0 | 0.67 ± 0 | 1.82 ± 0 | 0.70 ± 0 | 1.99 ± 0 | 0.97 ± 0 | 2.31 ± 0 |
Pmus (cmH2O) | -6.7 | -29.7 | -8.6 | -20.4 | -9.1 | -22.7 | -13.0 | -28.6 |
∆t(Q2−Q1) (ms) | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0 ± 0 | ||||