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Table 1 Clinical characteristics and CT features of patients in the training and test sets

From: A nomogram for predicting lymphovascular invasion in lung adenocarcinoma: a retrospective study

Characteristics

Training set

Test set

LVI-positive

(n = 171)

LVI-negative

(n = 145)

P value

LVI-positive

(n = 73)

LVI-negative

(n = 61)

P value

Age, years (mean ± SD)

56.90 ± 9.80

58.50 ± 9.70

0.144

57.50 ± 9.60

59.50 ± 9.50

0.227

Sex, n (%)

  

0.145

  

0.094

 Male

100 (58.50)

72 (49.70)

 

44 (60.30)

27 (44.30)

 

 Female

71 (41.50)

73 (50.30)

 

29 (39.70)

34 (55.70)

 

Smoking history, n (%)

  

0.506

  

0.776

 No

112 (65.50)

101 (69.70)

 

53 (72.60)

42 (68.90)

 

 Yes

59 (34.50)

44 (30.30)

 

20 (27.40)

19 (31.10)

 

CEA(ng/mL), n (%)

  

P < 0.001

  

0.030

≤ 5

86 (50.30)

110 (75.90)

 

45 (61.60)

49 (80.30)

 

> 5

85 (49.70)

35 (24.10)

 

28 (38.40)

12 (19.70)

 

Diameter(cm), (mean ± SD)

3.10 ± 1.30

2.00 ± 0.90

P < 0.001

3.20 ± 1.50

2.20 ± 0.90

P < 0.001

Location, n (%)

  

0.384

  

0.040

 Left lung

79 (46.20)

59 (40.70)

 

21 (28.80)

29 (47.50)

 

 Right lung

92 (53.80)

86 (59.30)

 

52 (71.20)

32 (52.50)

 

Border, n (%)

  

1.000

  

0.506

 Sharp

149 (87.10)

127 (87.60)

 

65 (89.00)

51 (83.60)

 

 Ill-defined

22 (12.90)

18 (12.40)

 

8 (11.00)

10 (16.40)

 

Shape, n (%)

  

0.243

  

0.925

 Regular

82 (48.00)

80 (55.20)

 

39 (53.40)

34 (55.70)

 

 Irregular

89 (52.00)

65 (44.80)

 

34 (46.60)

27 (44.30)

 

Spiculation, n (%)

  

P < 0.001

  

P < 0.001

 Absent

56 (32.70)

87 (60.00)

 

20 (27.40)

39 (63.90)

 

 Present

115 (67.30)

58 (40.00)

 

53 (72.60)

22 (36.10)

 

Lobulation, n (%)

  

P < 0.001

  

P < 0.001

 Absent

43 (25.10)

66 (45.50)

 

14 (19.20)

31 (50.80)

 

 Present

128 (74.90)

79 (54.50)

 

59 (80.80)

30 (49.20)

 

Vacuole sign, n (%)

  

0.025

  

0.358

 Absent

162 (94.70)

126 (86.90)

 

67 (91.80)

52 (85.20)

 

 Present

9 (5.30)

19 (13.10)

 

6 (8.20)

9 (14.80)

 

Air bronchogram, n (%)

  

0.177

  

0.306

 Absent

165 (96.50)

134 (92.40)

 

71 (97.30)

56 (91.80)

 

 Present

6 (3.50)

11 (7.60)

 

2 (2.70)

5 (8.20)

 

Pleural indentation, n (%)

  

0.947

  

1.000

 Absent

82 (48.00)

71 (49.00)

 

33 (45.20)

28 (45.90)

 

 Present

89 (52.00)

74 (51.00)

 

40 (54.80)

33 (54.10)

 
  1. Data in parentheses are percentages
  2. LVI Lymphovascular invasion, SD Standard deviation, CEA Carcinoembryonic antigen