Stage 0 | Stage 1 | Stage 2 | Stage 3 + Stage 4 | P | |
---|---|---|---|---|---|
Irisin | 3,73 (3,1-3,9) | 3,22 (2,9–3,7) | 3,32 (3,1–4,1) | 3,07 (2,6-4,5) | 0,533 |
Adiponectin | 7,45 (6,3-8,1) | 7,46 (5,7–10,1) | 7,90 (6,1-10,7) | 7,78 (5,8-31,2) | 0,945 |
ACE | 79 (25–142) | 70,50 (28,2-79,5) | 55 (44–65) | 73 (60–90) | 0,781 |
Calcium | 9 (8,5–9,6) | 9 (8,9–9,5) | 9,3 (9–9,52) | 9,60(9,0–9,7) | 0,047 |
BAL lymphocyte% | 42 (29–44) | 40 (19,2–54,4) | 40 (27,5–48,5) | 37 (25–45) | 0,973 |
CD4/CD8 | 5 (2,1–6,5) | 5,5 (4,1–7,7) | 5 (3,2–9) | 4,5 (3,0–6) | 0,819 |
FEV1/FVC | 85 (76–88) | 80 (73,5–83,2) | 78 (73,5–88) | 81 (72–83) | 0,693 |
FVC | 3,0 (3–3,3) | 3,5 (2,6–4,1) | 2,7 (2,2–3,79) | 3,42(2,5–4,1) | 0,601 |
FVC % | 107 (98–117) | 105 (87–112,5) | 88 (74–102,5) | 81 (77,5–102,5) | 0,094 |
FEV1 | 2,45 (2,2-2,7) | 2,65 (2,1–3,3) | 2,18 (1,6–2,6) | 2,42 (1,9-3,3) | 0,310 |
FEV1% | 97 (92–119) | 95 (77–105,5) | 79 (70–96,5) | 79 (75–99) | 0,130 |
DLCO% | 85 (73–99) | 84 (71–99) | 75 (56–95) | 67 (59–71) | 0,036 |