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Table 1 Clinical characteristics and demographic

From: Preoperative fractional exhaled nitric oxide is a risk and predictive factor of postoperative cough for early-stage non-small cell lung cancer patients: a longitudinal study

Variable

Cough(n = 138)

Non-cough (n = 154)

t/χ2/Z value

P value

Age, n (%)

    

≥ 60 years

85(61.5)

77(50.0)

3.961a

0.047

< 60 years

53(38.5)

77(50.0)

  

Gender, n (%)

    

Male

49(35.5)

52(33.8)

0.098a

0.755

Female

89(64.5)

102(66.2)

  

Preoperative lung function

    

FEV1(L)

2.22 ± 0.45

2.24 ± 0.46

-0.160b

0.873

FVC(L)

2.79 ± 0.53

2.82 ± 0.49

-0.390b

0.697

FENO (ppb)

34(19,40)

18(13,24)

-8.075c

< 0.001

Past medical history, n (%)

    

Hypertension

41(29.7)

43(27.9)

0.114a

0.736

Coronary heart disease

6(4.3)

6(3.9)

0.038a

0.846

Diabetes mellitus

27(19.6)

19(12.3)

2.705a

0.100

COPD

20(14.5)

16(10.4)

1.134a

0.287

Smoking history

25(18.1)

24(15.6)

0.334a

0.563

Duration of anesthesia (min)

195(160,230)

170(140,200)

-4.253c

< 0.001

Surgical side, n (%)

    

Right

81(58.7)

88(57.1)

0.072a

0.788

Left

57(41.3)

66(42.9)

  

Extent of surgery, n (%)

    

Lobectomy

72(52.2)

75(48.7)

0.351a

0.554

Sublobectomy

66(47.8)

79(51.3)

  

Pathology, n (%)

    

Adenocarcinoma

133(96.4)

148(96.1)

0.015a

0.903

Squamous carcinoma

5(3.6)

6(3.9)

0.015a

0.903

AIS or MIA

59(42.8)

85(55.2)

4.507a

0.036

  1. a Data are presented as No. (%) and χ2 test. b Data are presented as mean ± SD and t test .c Data are presented as median (IQR) and Mann-Whitney U test
  2. FEV1, forced expiratory volume in one second; FVC, forced vital capacity; FENO, fractional exhaled nitric oxide; COPD, chronic obstructive pulmonary disease; AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; SD, standard deviation; IQR, interquartile range