Table 3 Surgical outcomes
Variables | Unmatched cases | Matched cases | ||||
|---|---|---|---|---|---|---|
< 65Y, n = 45 | ≥ 65Y, n = 64 | P-value | < 65Y, n = 41 | ≥ 65Y, n = 36 | P-value | |
Time from first treatment to surgery, median (IQR), day | 80.7 (53.0-101.0) | 80.9 (51.0-100.8) | 0.638 | 72.0 (52.5-101.5) | 60.0 (51.3–99.3) | 0.675 |
Surgical approach, n (%) | 0.953 | 0.603 | ||||
Open | 26 (57.8) | 35 (54.7) | 25 (61.0) | 18 (50.0) | ||
VATS | 12 (26.7) | 16 (25.0) | 10 (24.4) | 8 (22.2) | ||
RATS | 1 (2.2) | 2 (3.1) | 1 (2.4) | 2 (5.6) | ||
VATS-Open | 6 (13.3) | 11 (17.2) | 5 (12.2) | 8 (22.2) | ||
Surgical method, n (%) | 0.624 | 0.841 | ||||
Wedge resection | 1 (2.2) | 3 (4.7) | 1 (2.4) | 1 (2.8) | ||
Lobectomy | 24 (53.3) | 33 (51.6) | 21 (51.2) | 17 (47.2) | ||
Sleeve resection | 14 (31.1) | 21 (32.8) | 13 (31.7) | 14 (38.9) | ||
Total pneumonectomy | 4 (8.9) | 7 (10.9) | 4 (9.8) | 4 (11.1) | ||
Segmental resection | 2 (4.4) | 0 (0.0) | 2 (4.9) | 0 (0.0) | ||
Operation time, median (IQR), min | 139.0 (107.0-175.0) | 147.0 (106.0-196.0) | 0.418 | 144.0 (109.0-175.0) | 156.5 (124.8-216.8) | 0.073 |
Estimated blood loss, median (IQR), mL | 50.0 (20.0-57.5) | 50.0 (20.0–60.0) | 0.645 | 50.0 (35.0–90.0) | 50.0 (20.0-57.5) | 0.524 |
Resection margin, n (%) | 1.000 | 1.000 | ||||
R0 | 42 (93.3) | 60 (93.8) | 39 (95.1) | 34 (94.4) | ||
R1 | 3 (6.7) | 4 (6,3) | 2 (4.9) | 2 (5.6) | ||
Number of lymph node dissections during surgery, median (IQR), n | 14.0 (10.0–21.0) | 17.0 (11.0–25.0) | 0.221 | 14.0 (10.0–23.0) | 18.0 (12.3–25.8) | 0.104 |
Length of hospital stay, median (IQR), day | 9.5 (7.0–14.0) | 14.0 (9.0–17.0) | 0.009 | 10.0 (7.0–14.0) | 14.0 (9.0–18.0) | 0.029 |
Postoperative complication, n (%) | ||||||
Overall | 14 (31.1) | 32 (50.0) | 0.049 | 14 (34.1) | 18 (50.0) | 0.159 |
Hydropneumothorax | 3 (6.7) | 6 (9.4) | 0.879 | 3 (7.3) | 3 (8.3) | 1.000 |
Hydrothorax | 8 (17.8) | 20 (31.3) | 0.113 | 8 (19.5) | 11 (30.6) | 0.262 |
Pneumothorax | 4 (8.9) | 4 (6.3) | 0.883 | 4 (9.8) | 3 (8.3) | 1.000 |
Chylothorax | 0 (0.0) | 1 (1.6) | 1.000 | 0 (0.0) | 1 (2.8) | 0.948 |
Bronchial obstruction | 0 (0.0) | 1 (1.6) | 1.000 | 0 (0.0) | 1 (2.8) | 0.948 |
Postoperative bleeding | 0 (0.0) | 1 (1.6) | 1.000 | 0 (0.0) | 1 (2.8) | 0.948 |
Pathological grade, n (%) | 0.268 | 0.152 | ||||
G1 | 0 (0.0) | 1 (1.6) | 0 (0.0) | 1 (2.8) | ||
G2 | 6 (13.3) | 16 (25.0) | 6 (14.6) | 11 (30.6) | ||
G3 | 17 (37.8) | 25 (39.1) | 15 (36.6) | 13 (36.1) | ||
Unknown | 22 (48.9) | 22 (34.4) | 20 (48.8) | 11 (30.6) | ||
ypTNM stage, n (%) | 0.277 | 0.137 | ||||
0 | 20 (44.4) | 17 (26.6) | 19 (46.3) | 8 (22.2) | ||
IA | 9 (20.0) | 16 (25.0) | 8 (19.5) | 7 (19.4) | ||
IB | 2 (4.4) | 4 (6.3) | 2 (4.9) | 2 (5.6) | ||
IIA | 1 (2.2) | 2 (3.1) | 1 (2.4) | 2 (5.6) | ||
IIB | 6 (13.3) | 18 (28.1) | 5 (12.2) | 12 (33.3) | ||
IIIA | 7 (15.6) | 6 (9.4) | 6 (14.6) | 4 (11.1) | ||
IIIB | 0 (0.0) | 1 (1.6) | 0 (0.0) | 1 (2.8) | ||