Table 3 Biological characteristics of patients with sarcoidosis with R ≥ 3.5 and R < 3.5

Biological data [median (IQR)]*

 Total lymphocytes count × 10⁹/L

1.22 (0.87–1.74)

1.17 (0.80–1.60)

1.28 (0.97–1.79)

1.30–2.70

0.125

  —B cells × 10⁹/L

0.35 (0.23–0.51)

0.32 (0.24–0.50)

0.36 (0.22–0.51)

0.29–0.80

0.987

  —T cells × 10⁹/L

0.81 (0.54–1.25)

0.73 (0.42–1.14)

0.90 (0.60–1.27)

0.70–2.10

0.243

  —CD4 cells × 10⁹/L

0.52 (0.31–0.83)

0.51 (0.25–0.83)

0.54 (0.37–0.86)

0.50–1.30

0.470

  —CD8 cells × 10⁹/L

0.23 (0.14–0.37)

0.19 (0.10–0.32)

0.29 (0.19–0.43)

0.20–0.70

0.060

  —CD4/CD8 ratio

2.10 (1.60–2.90)

2.40 (1.80–2.90)

2.00 (1.50–2.50)

0.175

 T cells activated × 10⁹/L

0.13 (0.07–0.17)

0.09 (0.06–0.15)

0.15 (0.1–0.21)

0.03–0.27

0.152

  —% among total lymphocytes

9.58 (6.65–16.00)

9.18 (6.74–12.36)

14.3 (6.62–20.1)

2.10–13.7

0.332

  —% among T cell

16.20 (10.40–23.50)

13.55 (11.00–17.20)

20.50 (9.55–29.00)

2.80–17.7

0.346

 CD4 + T-cell activated × 10⁹/L

0.06 (0.04–0.10)

0.05 (0.03–0.11)

0.06 (0.05–0.10)

0.02–0.08

0.727

  —% among total lymphocytes

5.03 (3.30–8.20)

5.01 (3.20–8.30)

5.03 (3.50–8.00)

1.00–4.30

0.836

  —% among CD4

12.80 (8.30–17.90)

14.55 (7.00–17.70)

12.30 (10.20–18.10)

2.10–10.40

0.970

 CD8 + T-cell activated × 10⁹/L

0.05 (0.030–0.10)

0.03 (0.02–0.07)

0.07 (0.05–0.12)

0.01–0.17

0.014

  —% among total lymphocytes

4.22 (2.40–8.80)

2.99 (2.20–5.70)

7.06 (3.70–11.60)

0.70–9.90

0.069

  —% among CD8

26.28 (14.60–37.30)

21.10 (12.50–30.10)

32.8 (18.10–42.10)

3.00–33.50

0.125

 ACE IU/L

66.0 (44.0–102.0)

73.0 (50.0–108.0)

54.5 (41.5–88.0)

20.0–70.0

0.082