Table 3 The microbiological, laboratory, and CT thorax findings of ILD patients in the IPA and non-IPA groups
Factors | IPA group (n = 58) | Non-IPA group (n = 295) | P value |
|---|---|---|---|
Laboratory findings | |||
WBC count (×109) | 11.1 ± 6.8 | 8.3 ± 3.3 | < 0.001 |
Neutrophils | 9.6 ± 6.8 | 6.2 ± 3.2 | < 0.001 |
Lymphocyte | 1.0 ± 0.6 | 1.5 ± 0.9 | < 0.001 |
NLR | 16.3 ± 17.3 | 6.4 ± 6.8 | < 0.001 |
Eos | 0.06 ± 0.10 | 0.12 ± 0.16 | 0.004 |
Hb | 116.8 ± 18.4 | 124.2 ± 18.6 | 0.006 |
Alb | 32.3 ± 4.3 | 35.3 ± 3.9 | < 0.001 |
LDH (U/L) | 379.2 ± 188.5 | 290.4 ± 116.1 | < 0.001 |
CRP (mg/L) | 84.8 ± 87.6 | 28.1 ± 38.5 | < 0.001 |
ESR (mm/h) | 45.7 ± 24.5 | 37.1 ± 25.1 | 0.038 |
PCT (ng/mL) | 1.06 ± 4.10 | 0.14 ± 0.49 | 0.001 |
IL-6 (ng/L) | 76.2 ± 169.1 | 24.8 ± 58.6 | < 0.001 |
CD4+(×109) | 312.7 ± 257.1 | 552.9 ± 386.0 | < 0.001 |
CD4+ (%) | 30.4 ± 12.6 | 35.6 ± 12.5 | 0.005 |
CD8+(×109) | 365.3 ± 334.8 | 433.7 ± 290.7 | 0.130 |
CD8+ (%) | 35.0 ± 16.3 | 29.9 ± 12.1 | 0.010 |
CD4+/CD8+ | 1.2 ± 1.0 | 1.5 ± 1.0 | 0.048 |
T3 | 2.3 ± 1.0 | 3.4 ± 1.8 | < 0.001 |
T4 | 14.0 ± 4.0 | 15.4 ± 4.3 | 0.058 |
TSH | 1.5 ± 2.8 | 2.7 ± 4.9 | 0.165 |
P/F ratio | 238.6 ± 111.9 | 307.4 ± 110.8 | 0.005 |
HRCT patterns | |||
UIP | 36 (62.1) | 137 (46.4) | 0.030 |
NSIP | 16 (27.6) | 110 (37.3) | 0.159 |
OP | 3 (5.2) | 20 (6.8) | 1.000 |
NSIP + OP | 3 (5.2) | 28 (9.5) | 0.445 |
CT thorax findings | |||
Reticulation | 51 (87.9) | 230 (88.8) | 0.085 |
Honeycombing | 40 (69.0) | 144 (48.8) | 0.005 |
Consolidation | 26 (44.8) | 89 (30.2) | 0.029 |
GGO | 45 (77.6) | 190 (64.4) | 0.052 |
Traction bronchiectasis | 49 (84.5) | 224 (75.9) | 0.155 |
Pleural effusion | 14 (24.1) | 39 (13.2) | 0.033 |
Air crescent sign | 1 (1.7) | 0 | 0.164 |