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Table 1 Basic information of selected SNPs

From: Integrating genetic and clinical data to predict lung cancer in patients with chronic obstructive pulmonary disease

SNPs

Gene

Allele

Location

Function

rs7689420

HHIP

C/T

4:144647200

intron

rs1489759

HHIP

A/G

4:144553321

intron

rs10519717

HHIP

T/C

4:144559188

intron

rs6495309

CHRNA3

C/T

15:78622903

upstream

rs12910984

CHRNA3

A/G

15:78599285

intron

rs2202507

GYPA

T/G

4:144336529

intron

rs56113850

CYP2A6

T/C

19:40847202

intron

rs7326277

FLT1

T/C

13:28302077

3’ UTR

rs2072493

TLR5

T/C

1:223111257

missense

rs1356888

NRXN1

C/T

2:50288880

intron

rs9224

FAM13A

G/A

4:88728508

3’ UTR

rs4796793

STAT3

C/G

17:42390192

upstream

rs3744483

STAT3

T/C

17:42314420

3’ UTR

rs1053005

STAT3

T/C

17:42313892

3’ UTR

rs2293152

STAT3

C/G

17:42329511

intron

rs696

NFKBIA

C/T

14:35401887

3’ UTR

rs8904

NFKBIA

G/A

14:35402011

3’ UTR

rs2273650

NFKBIA

C/T

14:35401592

3’ UTR

rs1799964

TNF

T/C

6:31574531

upstream

rs1800630

TNF

C/A

6:31574699

upstream

  1. SNPs: single nucleotide polymorphisms; HHIP: hedgehog interacting protein; CHRNA3: cholinergic receptor, neuronal nicotinic, α-polypeptide 3; GYPA: glycophorin A; CYP2A6: cytochrome P450 2A6; FLT1: vascular endothelial growth factor receptor 1; TLR5: toll like receptor 5; NRXN1: neurexin 1; FAM13A: family with sequence similarity 13 member A; STAT3: signal transducer and activator of transcription 3; NFKBIA: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor alpha; TNF: tumor necrosis factor