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Table 4 DEGs of monocyte/macrophage with |Fold change|>=1.2 and p-value < 0.05

From: Single cell transcriptomics in blood of patients with chronic obstructive pulmonary disease

Gene

p-value

Fold change

pct.1

pct.2

p_val_adj

FOLR3

0

-1.61601723

0.104

0.419

0

CD52

1.07E-180

-1.33544358

0.521

0.743

3.92E-176

RPS4Y1

2.01E-151

-1.32380721

0.395

0.683

7.35E-147

TMEM176B

1.06E-130

-1.25889673

0.478

0.703

3.87E-126

HLA-DRB5

8.20E-118

1.22836361

0.801

0.657

3.00E-113

NAMPT

6.24E-117

1.27072085

0.676

0.461

2.28E-112

TMEM176A

8.90E-115

-1.25027853

0.418

0.644

3.26E-110

EGR1

8.91E-111

1.2896648

0.382

0.178

3.26E-106

NR4A1

4.86E-105

1.29614348

0.432

0.229

1.78E-100

CCL3

5.70E-105

1.35998206

0.489

0.287

2.09E-100

CXCL8

3.71E-104

1.33145698

0.342

0.15

1.36E-99

PTGS2

3.75E-102

1.26310306

0.308

0.122

1.37E-97

CD83

4.12E-93

1.24187736

0.515

0.315

1.51E-88

BCL2A1

1.56E-92

1.24669472

0.477

0.281

5.70E-88

SGK1

5.89E-90

1.25023228

0.594

0.408

2.16E-85

IL1B

9.45E-81

1.27457393

0.533

0.351

3.46E-76

BTG2

4.58E-79

1.22516768

0.562

0.402

1.68E-74

NFKBIZ

6.56E-78

1.22382692

0.626

0.474

2.40E-73

DUSP2

1.77E-74

1.26143133

0.413

0.25

6.49E-70

MAFB

1.51E-70

1.22154038

0.605

0.459

5.54E-66

PLAUR

5.92E-70

1.20258311

0.601

0.439

2.17E-65

CCL3L1

4.50E-55

1.20903763

0.525

0.352

1.65E-50

  1. Note Fold Change: fold-change of the average expression between the two groups. Positive values indicate that the feature is more highly expressed in the COPD group
  2. pct.1: The percentage of cells where the feature is detected in the COPD group
  3. pct.2: The percentage of cells where the feature is detected in the normal control group
  4. p_val_adj: Adjusted p-value, based on bonferroni correction using all features in the dataset