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Table 1 Baseline and perioperative characteristics before and after IPTW-EW adjustment

From: The superiority of veno-arterial over veno-venous extracorporeal membrane oxygenation for operative support of lung transplantation

 

Original cohort

IPTW-EW cohort

 

V-A ECMO

(n = 29)

V-V ECMO

(n = 33)

p value

V-A ECMO

V-V ECMO

p value

Age, years

59 (54, 69)

61 (53, 65)

0.994

59 (53, 69)

61 (56, 66)

0.65

Male, n (%)

27 (93)

30 (91)

1.000

11.0 (95)

12.6 (94)

0.869

BMI, kg/m2

20.3 (4.8)

21.8 (4.1)

0.209

21.1 (5.1)

22.2 (3.3)

0.513

Indication, n (%)

      

 Pulmonary Fibrosis

8 (28)

18 (55)

0.059

4.4 (38)

4.3 (32)

0.762

 COPD

21 (72)

15 (45)

 

7.2 (62)

9.0 (68)

 

Underlying disease, n (%)

      

 Diabetes

6 (21)

3 (9)

0.351

1.6 (14)

3.3 (25)

0.506

 Hypertension

3 (10)

7 (21)

0.415

0.9 (8)

2.8 (21)

0.321

 Coronary heart disease

4 (14)

7 (21)

0.667

1.4 (12)

2.4 (18)

0.659

Blood type, n (%)

      

 A

7 (24)

11 (33)

0.864

2.5 (21)

2.1 (15)

0.919

 B

10 (35)

9 (27)

 

1.7 (14)

1.2 (9)

 

 AB

3 (10)

3 (9)

 

3.0 (26)

3.9 (29)

 

 O

9 (31)

10 (30)

 

4.4 (38)

6.2 (46)

 

NYHA, n (%)

      

 I

13 (45)

12 (36)

0.785

4.5 (39)

2.9 (21)

0.252

 II

14 (48)

18 (55)

 

6.1 (53)

10.2 (76)

 

 III

2 (7)

3 (9)

 

0.9 (8)

0.3 (2)

 

Echocardiography

      

 LVEF, %

67 (5)

66 (5)

0.789

66 (5)

64 (5)

0.319

 RV Enlargement, n (%)

7 (24)

10 (30)

0.797

3.7 (32)

1.5 (11)

0.114

 Tricuspid regurgitation, n (%)

      

 mild

24 (83)

29 (88)

0.836

9.0 (78)

10.0 (75)

0.964

 moderate

4 (14)

3 (9)

 

1.7 (15)

1.9 (14)

 

 severe

1 (3)

1 (3)

 

0.9 (8)

1.4 (11)

 

 SPAP, mmHg

35 (9)

35 (8)

0.969

38 (9)

36. (6)

0.416

Ventilation preoperatively, n (%)

6 (21)

7 (21)

1.000

1.7 (15)

2.4 (18)

0.789

Blood gas preoperatively

      

 pH

7.39 (7.35, 7.43)

7.40 (7.37, 7.44)

0.358

7.41 (7.38, 7.43)

7.40 (7.36, 7.44)

0.717

 PaO2, mmHg

203 (160, 269)

147 (115, 220)

0.124

164 (95, 219)

180 (131, 265)

0.313

 PaCO2, mmHg

64 (44, 68)

45 (40, 64)

0.209

45 (37, 62)

45 (37, 63)

0.905

Intraoperative information

      

 Transplantation method, n (%)

      

 Single

25 (86)

19 (58)

0.028

8.4 (73)

10.7 (80)

0.661

 Bilateral

4 (14)

14 (42)

 

3.1 (27)

2.6 (20)

0.661

 Surgery time, min

390 (330, 440)

360 (300, 400)

0.043

331 (290, 420)

360 (360, 370)

0.612

 Donor lung ischemia time, min

600 (520, 630)

490 (395, 540)

0.001

540 (515, 600)

540 (480, 596)

0.96

 Fluid intake, ml

2700 (2320, 3000)

2910 (2020, 3520)

0.572

2519 (2271, 2905)

2713 (2000, 3005)

0.669

 Fluid output, ml

3000 (2570, 3600)

2700 (2100, 3500)

0.175

2778 (2440, 3337)

2681 (2334, 2886)

0.663

 Urine volume, ml

1400 (800, 1600)

1600 (1200, 2000)

0.177

1200 (800, 1591)

1430 (848.39, 1700)

0.734

 Blood transfusion, ml

1070 (830, 1440)

1200 (600, 1440)

0.703

993 (800, 1240)

1011 (260, 1320)

0.323

  1. Data are presented as mean (standard deviation), median (interquartile ranges), or number (percentage) as appropriate
  2. APACHE: Acute Physiology and Chronic Health Evaluation; BMI: Body Mass Index; COPD: Chronic Obstructive Pulmonary Disease; ECMO: Extracorporeal Membrane Oxygenation; LVEF: Left Ventricular Ejection Fraction; NYHA: New York Heart Association; PaCO2: Partial pressure of arterial Carbon Dioxide; PaO2: Partial pressure of arterial Oxygen; RV: Right Ventricular; SPAP: Systolic Pulmonary Artery Pressure; V-A: Veno-Arterial; V-V: Veno-Venous