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Table 2 Postoperative parameters and clinical outcomes before and after IPTW-EW adjustment

From: The superiority of veno-arterial over veno-venous extracorporeal membrane oxygenation for operative support of lung transplantation

 

Original cohort

IPTW-EW cohort

 

V-A ECMO

(n = 29)

V-V ECMO

(n = 33)

p value

V-A ECMO

V-V ECMO

p value

Postoperative first ICU day

      

 APACHE II score

17.6 (5.9)

18.0 (5.5)

0.775

17 (5)

17 (6)

0.926

 SPAP, mmHg

30 (9)

40 (10)

< 0.001

30 (8)

37 (9)

0.007

 Lactate, mmol/L

3.2 (2.0, 5.2)

3.9 (2.4, 5.5)

0.568

1.9 (1.5, 3.5)

2.2 (1.6, 4.0)

0.933

 PaO2, mmHg

119 (104, 146)

97 (74, 123)

0.003

119 (102, 135)

78 (72, 103)

0.002

 Pulmonary edema on CXR, n (%)

      

  Grade 1

9 (31)

3 (9)

0.003

5.8 (50)

0.4 (3)

< 0.001

  Grade 2

18 (62)

16 (49)

 

5.2 (45)

5.0 (38)

 

  Grade 3

2 (7)

14 (42)

 

0.6 (5)

7.9 (59)

 

Post-operative complications, n (%)

      

 Re-exploration for bleeding

2 (7)

2 (6)

1.000

0.5 (4)

0.8 (6)

0.872

 PGD

2 (7)

3 (9)

1.000

0.9 (8)

1.3 (10)

0.969

 Thrombotic complication

9 (31)

16 (49)

0.255

3.0 (26)

5.7 (43)

0.340

 Bloodstream infection

4 (14)

12 (36)

0.083

0.9 (8)

4.4 (33)

0.072

 Tracheal anastomotic leakage

1 (3)

4 (12)

0.433

0.8 (7)

0.5 (4)

0.610

 AKI

12 (41)

21 (64)

0.134

4.9 (43)

8.7 (65)

0.244

Clinical outcomes

      

 ECMO duration, day

2 (1, 2)

2 (2, 3)

0.119

2 (1, 2)

2 (2, 4)

0.390

 RBC transfused with 7 day, U

4.0 (0, 5.5)

3.5 (1.5, 6.0)

0.954

2 (0, 6)

2 (0, 3)

0.582

 CRRT, n (%)

3 (10)

5 (15)

0.854

1.1 (10)

1.8 (13)

0.980

 LOMV, hour

161 (40, 665)

62 (35, 480)

0.485

43 (19, 309)

38 (25, 258)

0.417

 Tracheostomy, n (%)

11 (38)

12 (36)

1.000

2.6 (22)

5.0 (38)

0.360

 LOICU, day

7 (4, 10)

7 (5, 16)

0.343

6 (5, 9)

7 (4, 9)

0.986

 LOHS, day

43 (31, 56)

47 (32, 71)

0.568

37 (30, 43)

35 (33, 63)

0.533

 28-day mortality, n (%)

2 (7)

10 (30)

0.045

0.5 (5)

3.9 (29)

0.017

 Hospital mortality, n (%)

6 (21)

14 (42)

0.120

2.5 (21)

8.0 (69)

0.035

  1. Data are presented as mean (standard deviation), median (interquartile ranges), or number (percentage) as appropriate
  2. AKI (Acute Kidney Injury), CRRT (Continuous Renal Replacement Therapy), CXR (Chest X-Ray), ECMO (Extracorporeal Membrane Oxygenation), ICU (Intensive Care Unit), LOHS (Length of Hospital Stay), LOICU (Length of Intensive Care Unit stay), LOMV (Length of Mechanical Ventilation), PaO2 (Partial pressure of arterial Oxygen), PGD (Primary Graft Dysfunction), RBC (Red Blood Cell), SPAP (Systolic Pulmonary Artery Pressure), V-A (Veno-Arterial), V-V (Veno-Venous)