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Table 1 Clinical Data of patients with severe or non-severe psittacosis pneumonia

From: Clinical features and prognostic predictors of C. Psittaci Pneumonia: a systematic review and individual patient meta-analysis

Characteristic

Total(N = 566)

Severe (n = 292)

Non-severe (n = 274)

P-value

Age, y, median (IQR)

60(49, 69)

61(50, 69)

59(48, 68)

0.144

Male sex

341(60.2)

189(64.7)

152(55.5)

0.025

Poultry exposure

428(75.6)

221(75.7)

207(75.5)

0.970

Underlying diseaseaa

212(37.5)

126(43.2)

86(31.4)

0.004

Hypertension

105(18.6)

56(19.2)

49(17.9)

0.692

Diabetes

65(11.5)

44(15.1)

21(7.7)

0.006

Chronic cardiovascular diseases

41(7.2)

32(11.0)

9(3.3)

<0.001

Chronic hepatopathy

28(4.9)

15(5.1)

13(4.7)

0.830

Chronic respiratory disease

17(3.0)

11(3.8)

6(2.2)

0.272

Immunocompromised stateb

16(2.8)

5(1.7)

11(4.0)

0.099

Autoimmune disease

9(1.6)

3(1.0)

6(2.2)

0.269

Pregnancy

5(0.9)

5(1.7)

0(0)

0.030

Manifestation

    

Fever

545(96.3)

282(96.6)

263(96.0)

0.711

Cough

418(73.9)

225(77.1)

193(70.4)

0.073

Dyspnea

245(43.3)

188(64.4)

57(20.8)

<0.001

Fatigue

238(42.0)

124(42.5)

114(41.6)

0.836

Chills

202(35.7)

93(31.8)

109(39.8)

0.049

Myalgia

120(21.2)

50(17.1)

70(25.5)

0.014

Neuropsychiatric symptoms

114(20.1)

88(30.1)

26(9.5)

<0.001

Gastrointestinal symptom

158(27.9)

97(33.2)

61(22.3)

0.004

Headache

132(23.3)

60(20.5)

72(26.3)

0.107

Relative bradycardia

21(3.7)

15(5.1)

6(2.2)

0.064

Hemoptysis

38(6.7)

25(8.6)

13(4.7)

0.070

Rash

7(1.2)

3(1.0)

4(1.5)

0.642

Imaging

    

Multilobar infiltrates

318(56.2)

214(73.3)

104(38.0)

<0.001

Pleural effusion

251(44.3)

165(56.5)

86(31.4)

<0.001

Laboratory Examination

    

WBC ↑

N% ↑

129(22.8)

339(59.9)

75(25.7)

177(60.6)

54(19.7)

162(59.1)

0.090

0.717

Complication

    

Failure of respiration

292(51.6)

255(87.3)

37(13.5)

<0.001

Hepatic injury

295(52.1)

175(59.9)

120(43.8)

<0.001

Hyponatremia

109(19.3)

64(21.9)

45(16.4)

0.098

Shock

72(12.7)

71(24.3)

1(0.4)

<0.001

Renal injury

78(13.8)

69(23.6)

9(3.3)

<0.001

Coagulation disorders

45(7.9)

39(13.4)

6(2.2)

<0.001

Hypokalemia

60(10.6)

37(12.7)

23(8.4)

0.099

MODS

41(7.2)

40(13.7)

1(0.4)

<0.001

Cardiac insufficiency

38(6.7)

35(12.0)

3(1.1)

<0.001

Rhabdomyolysis

12(2.1)

9(3.1)

3(1.1)

0.101

Meningitis

6(1.1)

5(1.7)

1(0.4)

0.118

Hemophagocytic syndrome

2(0.4)

2(0.7)

0(0)

0.170

Outcomes

    

Invasive ventilation

183(32.3)

183(62.7)

0(0)

<0.001

CRRT

28(4.9)

28(9.6)

0(0)

<0.001

ECMO

30(5.3)

30(10.3)

0(0)

<0.001

Death

26(4.6)

26(8.9)

0(0)

<0.001

  1. Data are presented as No. (%) unless otherwise indicated
  2. Abbreviation: IQR, interquartile range
  3. aSome patients had several underlying diseases
  4. bImmunocompromised state: Solid malignant tumor, Hematologic malignancy, AIDS, Long-term oral glucocorticoids or immunosuppressive agents treatment, etc