BMC Pulmonary Medicine

Table 1 MR heterogeneity analysis results

From: Association between allergic rhinitis, nasal polyps, chronic sinusitis and chronic respiratory diseases: a mendelian randomization study

Exposure	Outcome (UKB database)	Method	Statistics Q	P value
Allergic rhinitis	asthma	MR Egger	157.899	< 0.001
Allergic rhinitis	asthma	IVW	158.858	< 0.001
Allergic rhinitis	COPD	MR Egger	79.186	0.263
Allergic rhinitis	COPD	IVW	81.003	0.244
Allergic rhinitis	ILD	MR Egger	219.557	< 0.001
Allergic rhinitis	ILD	IVW	219.607	< 0.001
Nasal polyps	COPD	MR Egger	12.525	0.639
Nasal polyps	COPD	IVW	12.574	0.704
Nasal polyps	bronchiectasis	MR Egger	9.943	0.445
Nasal polyps	bronchiectasis	IVW	13.439	0.266
Exposure	Outcome (FinnGen database)	Method	Statistics Q	P value
Allergic rhinitis	asthma	MR Egger	221.575	< 0.001
Allergic rhinitis	asthma	IVW	225.498	< 0.001
Allergic rhinitis	COPD	MR Egger	194.327	< 0.001
Allergic rhinitis	COPD	IVW	196.872	< 0.001
Allergic rhinitis	ILD	MR Egger	155.747	0.007
Allergic rhinitis	ILD	IVW	156.728	0.007
Nasal polyps	COPD	MR Egger	27.622	0.050
Nasal polyps	COPD	IVW	29.956	0.038
Nasal polyps	bronchiectasis	MR Egger	16.426	0.563
Nasal polyps	bronchiectasis	IVW	17.211	0.576

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ISSN: 1471-2466

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