Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.

Skip to main content

Table 2 The relationships between inflammatory markers and mortality in respiratory sarcopenia

From: The systemic inflammation response index as risks factor for all-cause and cardiovascular mortality among individuals with respiratory sarcopenia

Characteristic

Crude model

 

Model 1

 

Model 2

 

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

All-cause mortality

NLR

1.20(1.11,1.31)

 < 0.001

1.15(1.05,1.25)

0.002

1.13(1.02,1.25)

0.015

 NLR category

 Lower NLR (n = 1415)

Ref

 

Ref

 

Ref

 

 Higher NLR (n = 258)

1.86(1.41,2.47)

 < 0.001

1.64(1.23,2.19)

 < 0.001

1.45(1.07,1.97)

0.017

NMLR

1.20(1.11,1.30)

 < 0.001

1.14(1.05,1.24)

0.002

1.12(1.02,1.24)

0.016

 NMLR category

 Lower NMLR (n = 1386)

Ref

 

Ref

 

Ref

 

 Higher NMLR (n = 287)

1.98(1.51,2.59)

 < 0.001

1.75(1.33,2.32)

 < 0.001

1.51(1.13,2.03)

0.005

SIRI

1.39(1.22,1.58)

 < 0.001

1.24(1.09,1.42)

0.001

1.18(1.02,1.36)

0.024

 SIRI category

      

 Lower SIRI (n = 1386)

Ref

 

Ref

 

Ref

 

 Higher SIRI (n = 287)

1.99(1.53,2.61)

 < 0.001

1.78(1.35,2.36)

 < 0.001

1.65(1.23,2.22)

 < 0.001

Cardiovascular mortality

NLR

1.26(1.09,1.47)

0.002

1.23(1.04,1.45)

0.016

1.24(1.02,1.50)

0.03

 NLR category

 Lower NLR (n = 1263)

Ref

 

Ref

 

Ref

 

 Higher NLR (n = 215)

2.63(1.57,4.40)

 < 0.001

2.31(1.36,3.93)

0.002

1.93(1.09,3.42)

0.024

NMLR

1.25(1.09,1.44)

0.002

1.21(1.03,1.43)

0.019

1.22(1.02,1.46)

0.033

 NMLR category

 Lower NMLR (n = 1241)

Ref

 

Ref

 

Ref

 

 Higher NMLR (n = 237)

2.69(1.63,4.45)

 < 0.001

1.46(1.46,4.14)

 < 0.001

2.10(1.20,3.68)

0.01

SIRI

1.51(1.20,1.90)

 < 0.001

1.41(1.10,1.80)

0.006

1.42(1.08,1.86)

0.013

 SIRI category

 Lower SIRI (n = 1240)

Ref

 

Ref

 

Ref

 

 Higher SIRI (n = 238)

3.27(2.00,5.33)

 < 0.001

3.13(1.87,5.24)

 < 0.001

3.18(1.83,5.53)

 < 0.001

  1. Crude Model, unadjusted. Model 1, adjusted for age, sex, ethnicity, smoking status, drinking status, education level and annual household income. Model 2, adjusted for age, sex, ethnicity, smoking status, drinking status, education level, annual household income, BMI, diabetes, cardiovascular disease, stroke, hypertension, cancer history, eGFR, HDL, TG, TC and albumin. NLR neutrophil-to-lymphocyte ratio, NMLR neutrophil-monocyte-to-lymphocyte ratio, SIRI systemic inflammatory response index, BMI body mass index, HDL High density lipoprotein cholesterol, TC Cholesterol, TG Triglycerides, eGFR estimated glomerular filtration rate, HRs hazard ratios, CI confidence interval