Table 1 Data resources of the exposures and outcomes used in this study
GWAS traits | GWAS consortium | First author | Year | PMID | Population | Data type | Sample size | Case | Control |
|---|---|---|---|---|---|---|---|---|---|
Circulating Lipids | |||||||||
 LDL cholesterol | Global Lipids Genetics Consortium | Sarah E Graham | 2021 | 34887591 | European | Continuous | 1,320,016 | — | — |
 Total triglycerides | Global Lipids Genetics Consortium | Sarah E Graham | 2021 | 34887591 | European | Continuous | 1,320,016 | — | — |
Positive Control | |||||||||
 Coronary heart disease | CARDIoGRAMplusC4D | Nikpay | 2015 | 26343387 | European | Binary | 184,305 | 60,801 | 123,504 |
Respiratory Diseases | |||||||||
 Asthma | — | Valette K | 2021 | 34103634 | European | Binary | 408,442 | 56,167 | 352,255 |
 Idiopathic pulmonary fibrosis | — | Richard J A | 2022 | 35688625 | European | Binary | 24,589 | 4,125 | 20,464 |
 Chronic obstructive pulmonary disease | Finngen | — | — | — | European | Binary | 329,552 | 18,266 | 311,286 |
 Pulmonary oedema | MRC-IEU | — | 2021 | — | European | Binary | 216,556 | 193 | 216,363 |
 Pulmonary embolism | MRC-IEU | Mbatchou J | 2021 | 34017140 | European | Binary | 407,746 | — | — |
 Pulmonary eosinophilia | MRC-IEU | — | 2021 | — | European | Binary | 215,937 | 182 | 215,755 |
 Tuberculosis | MRC-IEU | Sakaue S | 2021 | 34594039 | European | Binary | 477,386 | 895 | 476,491 |