Table 2 Association of NPAR with lung function parameters

FENO

0.08 (0.07, 0.09) < 0.0001

0.08 (0.07, 0.08) < 0.0001

0.08 (0.07, 0.08) < 0.0001

Q1

Reference

Reference

Reference

Q2

1.46 (0.67, 2.25) 0.0003

1.16 (0.37, 1.94) 0.0040

1.13 (0.35, 1.90) 0.0044

Q3

3.23 (2.43, 4.03) < 0.0001

2.78 (1.98, 3.57) < 0.0001

2.97 (2.19, 3.76) < 0.0001

Q4

7.97 (7.17, 8.78) < 0.0001

7.32 (6.52, 8.13) < 0.0001

7.52 (6.72, 8.32) < 0.0001

P for trend

< 0.0001

< 0.0001

< 0.0001

FVC

-0.41 (-0.86, 0.04) 0.0765

-0.48 (-0.77, -0.20) 0.0008

-0.37 (-0.65, -0.10) 0.0076

Q1

Reference

Reference

Reference

Q2

-1.26 (-60.24, 57.72) 0.9666

-25.82 (-62.54, 10.89) 0.1681

-26.43 (-62.09, 9.22) 0.1462

Q3

-21.59 (-81.27, 38.09) 0.4784

-51.69 (-88.95, -14.42) 0.0066

-40.63 (-76.88, -4.38) 0.0281

Q4

-40.15 (-100.30, 20.00) 0.1908

-70.09 (-107.82, -32.37) 0.0003

-61.02 (-97.69, -24.34) 0.0011

P for trend

0.1378

0.0002

0.0013

FEV1

-0.92 (-1.29, -0.54) < 0.0001

-0.63 (-0.87, -0.40) < 0.0001

-0.52 (-0.75, -0.29) < 0.0001

Q1

Reference

Reference

Reference

Q2

-51.15 (-99.99, -2.31) 0.0401

-39.65 (-69.98, -9.33) 0.0104

-42.79 (-72.29, -13.29) 0.0045

Q3

-79.08 (-128.51, -29.65) 0.0017

-59.36 (-90.13, -28.58) 0.0002

-49.03 (-79.03, -19.04) 0.0014

Q4

-131.75 (-181.56, -81.93) < 0.0001

-98.16 (-129.32, -67.01) < 0.0001

-89.24 (-119.59, -58.89) < 0.0001

P for trend

< 0.0001

< 0.0001

< 0.0001

PEF

-1.00 (-1.92, -0.09) 0.0315

-1.58 (-2.26, -0.90) < 0.0001

-1.28 (-1.93, -0.63) 0.0001

Q1

Reference

Reference

Reference

Q2

-35.24 (-154.80, 84.33) 0.5635

-92.18 (-180.52, -3.84) 0.0409

-132.42 (-217.27, -47.57) 0.0022

Q3

-2.25 (-123.25, 118.75) 0.9709

-89.55 (-179.22, 0.11) 0.0503

-89.59 (-175.85, -3.32) 0.0418

Q4

-133.45 (-255.39, -11.50) 0.0320

-234.68 (-325.45, -143.91) < 0.0001

-236.63 (-323.91, -149.35) < 0.0001

P for trend

0.0350

< 0.0001

< 0.0001

FEF25%-75%

-2.13 (-2.67, -1.59) < 0.0001

-1.12 (-1.54, -0.70) < 0.0001

-0.99 (-1.40, -0.58) < 0.0001

Q1

Reference

Reference

Reference

Q2

-172.19 (-242.82, -101.56) < 0.0001

-91.96 (-146.18, -37.73) 0.0009

-105.50 (-158.76, -52.24) 0.0001

Q3

-214.00 (-285.48, -142.52) < 0.0001

-99.16 (-154.20, -44.11) 0.0004

-95.32 (-149.47, -41.17) 0.0006

Q4

-342.92 (-414.96, -270.88) < 0.0001

-184.20 (-239.92, -128.49) < 0.0001

-179.73 (-234.51, -124.94) < 0.0001

P for trend

< 0.0001

< 0.0001

< 0.0001

FEV1/FVC%

-0.02 (-0.02, -0.01) < 0.0001

-0.01 (-0.01, -0.00) < 0.0001

-0.01 (-0.01, -0.00) < 0.0001

Q1

Reference

Reference

Reference

Q2

-1.25 (-1.69, -0.81) < 0.0001

-0.48 (-0.87, -0.10) 0.0140

-0.58 (-0.96, -0.20) 0.0025

Q3

-1.55 (-1.99, -1.10) < 0.0001

-0.48 (-0.87, -0.09) 0.0169

-0.44 (-0.83, -0.06) 0.0224

Q4

-2.53 (-2.98, -2.08) < 0.0001

-1.11 (-1.51, -0.72) < 0.0001

-1.09 (-1.47, -0.70) < 0.0001

P for trend

< 0.0001

< 0.0001

< 0.0001