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Table 3 Hazard ratio of covariate of all-cause mortality

From: Incidence and clinical impact of coronary artery disease confirmed by coronary CT angiography in patients with interstitial lung disease

Variables

Univariate analysis

Multivariable analysis

HR (95% Cl)

P-Value

HR (95% Cl)

P-Value

Age*

1.05 (1.01 − 1.09)

0.009

1.04 (1.00 − 1.08)

0.035

Male sex

1.32 (0.63 − 2.78)

0.468

  

Body mass index†

0.89 (0.79 − 0.99)

0.033

1.01 (0.88 − 1.16)

0.932

Smoking history

0.78 (0.51 − 1.87)

0.948

  

IPF

2.32 (1.21 − 4.48)

0.012

1.58 (0.77 − 3.23)

0.209

Hypertension

1.77 (0.94 − 3.32)

0.077

1.25 (0.62 − 2.51)

0.529

Diabetes

1.24 (0.63 − 2.42)

0.529

  

FVC†

0.97 (0.95 − 0.98)

< 0.001

0.99 (0.97 − 1.02)

0.568

DLco†

0.97 (0.96 − 0.99)

< 0.001

0.97 (0.95 − 1.00)

0.016

TWI on ECG

1.07 (0.45 − 2.55)

0.882

  

LV ejection fraction†

1.01 (0.95 − 1.07)

0.875

  

Significant CAD

2.79 (1.46 − 5.33)

0.002

2.31 (1.07 − 5.01)

0.034

Agatston calcium score ≥ 40‡

5.21 (1.57–17.32)

0.007

  
  1. Analysis parameters with statistically significant differences are shown in bold
  2. *HR changes are shown for each 1-year increase in age
  3. †HR changes were shown for each 1 kg/m² decrease in BMI and each 1% decrease in predicted FVC and DLco
  4. ‡Agatston calcium score ≥ 40 (as a dichotomized variable) was not included in the multivariable analysis as scores were available for only 189 out of the total 215 patients
  5. CAD = coronary artery disease; CI = confidential interval; DLco = diffusing capacity for carbon monoxide; ECG = electrocardiogram; FVC = forced vital capacity; HR = hazard ratio; IPF = idiopathic pulmonary fibrosis; LV = left ventricle; TWI = T-wave inversion
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BMC Pulmonary Medicine

ISSN: 1471-2466

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