| Training | Validation | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 | Cluster 5 | Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 | Cluster 5 | |
GOLD_STAGE | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 0 | 131 (54%) | 83 (64%) | 83 (24%) | 6 (5.3%) | 1 (0.9%) | 123 (50%) | 82 (66%) | 84 (23%) | 4 (3.8%) | 0 (0%) |
 1 | 63 (26%) | 2 (1.5%) | 57 (17%) | 11 (9.7%) | 1 (0.9%) | 59 (24%) | 5 (4.0%) | 60 (17%) | 13 (12%) | 2 (1.9%) |
 2 | 18 (7.4%) | 20 (15%) | 142 (41%) | 47 (42%) | 29 (26%) | 35 (14%) | 18 (14%) | 158 (44%) | 37 (35%) | 22 (21%) |
 3 | 0 (0%) | 6 (4.6%) | 46 (13%) | 41 (36%) | 60 (54%) | 0 (0%) | 0 (0%) | 33 (9.2%) | 35 (33%) | 50 (49%) |
 4 | 0 (0%) | 0 (0%) | 4 (1.2%) | 8 (7.1%) | 20 (18%) | 0 (0%) | 0 (0%) | 5 (1.4%) | 17 (16%) | 29 (28%) |
Unknown†| 30 (12%) | 19 (15%) | 11 (3.2%) | 0 (0%) | 0 (0%) | 31 (13%) | 20 (16%) | 18 (5.0%) | 0 (0%) | 0 (0%) |
Exacerbation (%) | 52 (21%) | 47 (36%) | 155 (45%) | 76 (67%) | 88 (79%) | 56 (23%) | 43 (34%) | 182 (51%) | 72 (68%) | 79 (77%) |
Exacerbation (OR) | 1 | 2.069** | 3.012*** | 7.505*** | 13.980*** | 1 | 1.798* | 3.545*** | 7.261*** | 11.286*** |
Exacerbation (Adjusted OR) | 1 | 2.140** | 1.951** | 3.353*** | 4.621*** | 1 | 2.016** | 2.252*** | 2.711** | 3.091** |
Hazards ratio | 1 | 1.942** | 2.493*** | 4.906*** | 6.936*** | 1 | 1.620* | 2.662*** | 4.375*** | 5.680*** |