Table 1 The characteristics of all participants

Mean age(range)

61 ± 7

58 ± 6

2.819

0.057

Gender, male, n (%)

92(95.8%)

46(92.0%)

0.002

0.962

Smoking, n (%)

80(83.3%)

16(32.0%)

4.587

<0.001

Height(cm)

168.1 ± 5.9

169.5 ± 6.4

-1.370

0.173

Weight(kg)

72.9 ± 9.1

71.00 ± 8.2

1.259

0.210

BMI(m/kg²)

25.8 ± 2.6

24.7 ± 2.3

1.792

0.077

TLV on HRCT (L)

4.3 ± 0.9

4.7 ± 0.5

-2.511

0.013

Pulmonary function

FVC % predicted

82.9 ± 16.6

103.3 ± 11.0

-7.895

<0.001

FEV1% predicted

86.0 ± 15.8

99.1 ± 12.5

-5.118

<0.001

FEV1/FVC% predicted

82.6 ± 5.9

83.1 ± 9.9

-0.340

0.734

TLC% predicted

69.4 ± 13.9

98.5 ± 9.7

-13.325

<0.001

DLCO % predicted

54.9 ± 17.3

100.0 ± 14.1

-15.976

<0.001

6MWD(m)

495.5 ± 74.7

775.6 ± 49.5

-12.405

< 0.001

Resting dyspnea (MRC), n (%)

1

46(47.9%)

\

2

40(41.7%)

\

3

10(10.4%)

\

4

0

\

5

0

\

HRQoL

Respiratory symptoms

42.6 ± 23.7

\

Activity

51.8 ± 74.3

\

Psychosocial impact

19.5 ± 17.6

\

Total

30.0 ± 17.3

\

GAP score, n (%)

I

66(45.2%)

\

II

26(17.8%)

\

III

4(2.7%)

\

HRCT, n (%)

UIP

78(81.3%)

\

Possible UIP

18(18.7%)

\

The percentage of ILD findings on HRCT

GGO (%)

0.18 ± 0.9

\

Reticulation (%)

11.1 ± 8.9

\

Honeycombing (%)

8.7 ± 10.3

\

Pulmonary fibrosis (%)

19.8 ± 11.3

\