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Table 2 Association between categorical FEV1/FVC and mortality

From: Association between FEV1/FVC levels and all-cause mortality in the general population

FEV1/FVC

N

Model 1 (N = 25501)

Model 2 (N = 25501)

Model 3 (N = 25255)

Total

Death

HR (95%CI)

P value

HR (95%CI)

P value

HR (95%CI)

P value

0.90 ≤ FEV1/FVC ≤ 1.00

1303

176 (13.5%)

Reference

Reference

  

FEV1/FVC < 0.30

13

13 (100.0%)

48.56 (27.62–85.38)

< 0.001

5.03 (2.85–8.87)

< 0.001

3.53 (1.98–6.29)

< 0.001

0.30 ≤ FEV1/FVC < 0.40

67

55 (82.1%)

19.21 (14.18–26.02)

< 0.001

1.44 (1.06–1.96)

0.020

1.22 (0.89–1.68)

0.216

0.40 ≤ FEV1/FVC < 0.50

208

154 (74.0%)

15.26 (12.28–18.96)

< 0.001

1.35 (1.08–1.69)

0.007

1.25 (0.99–1.57)

0.060

0.50 ≤ FEV1/FVC < 0.60

636

415 (65.3%)

10.23 (8.57–12.21)

< 0.001

0.99 (0.83–1.19)

> 0.926

1.00 (0.83–1.20)

1.000

0.60 ≤ FEV1/FVC < 0.70

2706

1298 (48.0%)

6.23 (5.32–7.29)

< 0.001

0.79 (0.68–0.93)

0.005

0.80 (0.68–0.94)

0.007

0.70 ≤ FEV1/FVC < 0.80

9781

2718 (27.8%)

2.91 (2.50–3.39)

< 0.001

0.69 (0.59–0.80)

< 0.001

0.70 (0.60–0.81)

< 0.001

0.80 ≤ FEV1/FVC < 0.90

10,787

1602 (14.9%)

1.29 (1.10–1.51)

0.001

0.76 (0.65–0.88)

< 0.001

0.76 (0.65–0.88)

< 0.001

  1. Model 1: Unadjusted. Model 2: Adjusted for age, sex, BMI, race, and smoking status. Model 3: Adjusted for age, sex, BMI, race, smoking status, and comorbidities (congestive heart failure, stroke, asthma, chronic bronchitis, emphysema, cancer, diabetes, and hypertension). Abbreviations: HR = hazard ratio; CI = confidence interval; FEV1 = forced expiratory volume in 1 second; FVC = forced vital capacity