Ureaplasma in neonatal gastric fluid contributing to bronchopulmonary dysplasia

BMC Pulmonary Medicine

Table 3 Correlation between pathogens identified in maternal cervicovaginal swabs and neonatal clinical outcomes

	Group 1	Group 2	P value	Group 3	P value	Group 4	P value
	U-/O-, n = 40	U+/O-, n = 29		U+/O+, n = 24		U-/O+, n = 28
BPD, n (%)	11 (27.5%)	15 (51.7%)	0.048	13 (54.2%)	0.033	13 (46.4%)	n.s
--Moderate	1/11 (9.1%)	3/15 (20.0%)		0/13 (0%)		3/13 (23.1%)
--Severe	1/11 (9.1%)	6/15 (40.0%)		9/13 (69.2%)		4/13 (30.8%)
RDS, n (%)	28 (70.0%)	25 (86.2%)	n.s	19 (79.2%)	n.s	22 (78.6%)	n.s
-- RDS ≥ grade 3	4/28 (14.2%)	4/15 (26.7%)		6/19 (31.6%)		8/22 (36.4%)
NEC, n (%)	0 (0%)	2(6.9%)	n.s	5 (20.8%)	0.003	4 (14.3%)	0.014
ROP, n (%)	7 (17.5%)	6 (20.7%)	n.s	4 (16.7%)	n.s	8 (28.6%)	n.s
ICH, n (%)	7 (17.5%)	5 (17.2%)	n.s	5 (20.8%)	n.s	6 (21.4%)	n.s
Sepsis, n (%)	0 (0)	0 (0)	n.s	2 (8.3%)	n.s	6 (21.4%)	0.003
PDA requiring treatment, n (%)	4 (10.0%)	1 (3.4%)	n.s	1 (4.2%)	n.s	0 (0%)	n.s
Mortality, n (%)	2 (5.0%)	5 (17.2%)	n.s	4 (16.7%)	n.s	3 (10.7%)	n.s

BPD: bronchoplumonary dysplasia; Group 1: negative microorganism testing; Group 2: only Ureaplasma spp. identified; Group 3: positive testing for Ureaplasma spp. along with other microorganisms; Group 4: other microbes identified; ICH: Intracranial hemorrhage; NEC: necrotizing enterocolitis; O: other pathogens except for Ureaplasma spp; RDS: Respiratory distress syndrome; ROP: Retinopathy of prematurity; PDA: Patent ductus arteriosus; U: Ureaplasma spp
n.s: non-significant
P values applied to comparison with Group 1, respectively

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