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Table 1 Comparison of clinical features in detection with different types of pathogens and co-detection

From: Clinical characteristics of severe community-acquired pneumonia in children with virus mono-detection versus co-detection with bacteria

 

virusan = 172(%)

bacteriab

n = 41(%)

MP/CPcn = 85(%)

virus + bacteriadn = 51(%)

virus + MP/CPe

n = 20(%)

statistical measure

P value

Gender(male)

108(62.8)

30(73.2)

44(51.8)

33(64.7)

14(70.0)

χ2 = 147.9

0.152

Age(month)

20(11,36)ce

18(9,47)ce

76(53,98)abd

18

(11.5,41)ce

62.5 (36.25,79.5)abd

Z = 125.3*

0.000

Fever

140(81.4)bc

24(58.5)ace

83(97.6)abd

40(78.4)c

19(95.0)b

χ2 = 33.308

0.000

Cough

166(96.5)

39(95.1)

85(100)

50(98.0)

20(100)

F = 4.158

0.309

Expectoration

134(77.9)

35(85.4)

64(75.3)

43(84.3)

14(70.0)

χ2 = 3.585

0.465

Wheezing

82(47.7)c

22(53.7)ce

4(4.7)abd

26(51.0)c

3(15.0)b

χ2 = 59.661

0.000

Anhelation

53(30.8)c

11(26.8)

8(9.4)a

13(25.5)

3(15.0)

χ2 = 15.488

0.004

Vomiting

41(23.8)

8(19.5)

21(24.7)

13(25.5)

4(20.0)

χ2 = 0.688

0.953

Lung rale

71(41.3)

9(22.0)d

28(32.9)

27(52.9)b

9(45.0)

χ2 = 11.163

0.025

Atelectasis

39(22.7)

9(22.0)

22(25.9)

11(21.6)

5(25.0)

χ2 = 0.514

0.972

Pleural effusion

28(16.3)c

5(12.2)

29(34.1)ad

2(3.9)c

3(15.0)

χ2 = 23.049

0.000

Respiratory failure

6(3.5)

1(2.4)

4(4.7)

1(2.0)

1(5.0)

F = 1.244

0.881

Plastic bronchitis

16(9.3)

1(2.4)

10(11.8)

2(3.9)

4(20.0)

F = 7.233

0.105

WBC increase

76(44.2)c

22(53.7)c

22(25.9)abd

32(62.7)c

7(35.0)

χ2 = 20.784

0.000

WBC decrease

23(13.4)

1(2.4)e

9(10.6)

3(5.9)

6(30.0)b

χ2 = 12.382

0.015

Increased neutrophils ratio

36(20.9)c

6(14.6)c

38(44.7)abd

10(19.6)c

7(35.0)

χ2 = 22.26

0.000

CRP increase

90(52.3)c

15(36.6)c

67(78.8)ab

30(58.8)

11(55.0)

χ2 = 25.154

0.000

PCT increase

65(37.8)b

5(12.2)a

20(23.5)

17(33.3)

6(30.0)

χ2 = 12.906

0.012

ALT increase

4(2.3)

1(2.4)

5(5.9)

2(3.9)

1(5.0)

F = 2.918

0.532

AST increase

25(14.5)

3(7.3)

7(8.2)

4(7.8)

3(15.0)

χ2 = 4.094

0.393

LDH increase

142(82.6)

30(73.2)

68(80.0)

43(84.3)

17(85.0)

χ2 = 2.541

0.637

CK increase

30(17.4)

4(9.8)

16(18.8)

3(5.9)

1(5.0)

χ2 = 7.673

0.104

CK-MB increase

9(5.2)

2(4.9)

0(0.0)

4(7.8)

0(0.0)

F = 7.352

0.075

Antibiotics

166(96.5)

37(90.2)

84(98.8)

49(96.1)

20(100)

F = 5.331

0.192

Antiviral

48(27.9)

7(17.1)

13(15.3)

9(17.6)

7(35.0)

χ2 = 8.503

0.075

Corticosteroid

83(48.3)

19(46.3)

47(55.3)

22(43.1)

14(70.0)

χ2 = 5.54

0.236

Intravenous immunoglobulin

57(33.1)c

6(14.6)

12(14.1)a

9(17.6)

6(30.0)

χ2 = 15.719

0.003

Oxygen inhalation

96(55.8)bc

8(19.5)a

22(25.9)a

20(39.2)

7(35.0)

χ2 = 31.686

0.000

Mechanical ventilation

1(0.6)

1(2.4)

1(1.2)

0(0.0)

0(0.0)

F = 2.867

0.423

PICU administration

11(6.4)

1(2.4)

3(3.5)

1(2.0)

2(10.0)

F = 3.392

0.441

Duration of hospitalization

9(6,11)

8(6,9)

8(7,10)

9(7,10)

8.5(6.8,12.8)

Z = 5.259*

0.262

  1. a, b, c, d and e represented statistically significant differences between different groups, F refers to Fisher’s exact test, * indicated data that is not normally distributed, expressed as median (P25, P75), and the statistical measure was the Z value