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Table 1 Demographic, clinical, laboratory and radiological characteristics of patients with and without intensive care unit requirement due to COVID-19 disease

From: Diaphragm thickness and ICU admission risk in elderly COVID-19 patients: a CT-based analysis

 

Total

(n = 188)

Patients without ICU admission (n = 149, 79.3%)

Patients with ICU admission (n = 39, % 20.7)

p

Demographic data

    

Age (median) (min-max)

76(65–96)

75(65–96)

78(65–95)

0.180

Female gender, n (%)

95 (50.5)

75 (50.3)

20 (51.3)

0.916x

Clinical data

    

Duration of hospitalisation (days) (Median)(min-max)

12 (3–40)

10 (3–36)

16 (6–40)

< 0.001m

Presence of oxygen requirement, n (%)

122 (64.9)

88 (59.1)

34 (87.2)

0.001x

Exitus, n (%)

33 (17.6)

12 (8.1)

21 (53.8)

< 0.001x

Additional diseases

    

Hypertension, n (%)

142 (75.5)

112 (75.2)

30 (76.9)

0.820x

Diabetes Mellitus, n (%)

76 (40.4)

60 (40.3)

16 (41)

0.932x

COPD:, n (%)

55 (29.3)

42 (28.2)

13 (33.3)

0.529x

CAD, n (%)

85 (45.2)

65 (43.6)

20 (51.3)

0.392x

Dementia, n (%)

19 (10.1)

15 (10.1)

4 (10.3)

0.972x

Hypothyroidism, n (%)

15 (8)

12 (8.1)

3 (7.7)

0.941f

Chronic renal failure, n (%)

18 (9.6)

12 (8.1)

6 (15.4)

0.166f

Laboratory data

    

Lymphocyte (109/L) (Median)(min-max)

920 (160–8210)

960 (160–8210)

800 (330–2770)

0.500m*

CRP ( gr/L) (median)(min-max)

78 (1-291)

82.6 (1-269)

56.6 (5.5–291)

0.219m

Procalcitonin (μg/L) (median)(min-max)

0.1 (0–20)

0.1 (0–20)

0.2 (0.03–2.5)

0.019m

Maximum ferritin level (μg/L) (Median)(min-max)

571 (24-29467)

543 (24-12391)

989 (47-29467)

0.006m

Lactate (mmol/L) (Median)(min-max)

1.6 (0.02–4.9)

1.6 (0.02–4.9)

1.5 (0.5–3.7)

0.197m

Maximum interleukin-6 level (pg/mL) (median)(min-max)

571 (24-29467)

26.3 (0.1–759)

33.3 (3.6–1000)

0.048m

Radiological findings

    

Right DT (mm) (Mean ± SD)

1.8 ± 0.4

1.7 ± 0.4

2 ± 0.4

0.011t

Left DT (mm) (Mean ± SD)

1.8 ± 0.4

1.8 ± 0.4

1.8 ± 0.4

0.342t

  1. COVID-19: coronavirüs Disease 19 COPD: Chronic Obstructive Pulmonary Disease, CAD: Coronary Artery Disease, CRP: C reactive protein, DT: diaphragm thickness, m: Mann Whitney U Testi, t: Student’t T Testi x: Ki-kare Testi, f: Fisher’s Exact Testi