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Table 1 Baseline characteristics of the study population grouped by GNRI (n = 1,153)

From: Association between the geriatric nutritional risk index and adverse post-extubation outcomes for critically ill older adults: a retrospective study

Characteristics

Total

GNRI

P for trend

<82 (n = 328)

82 ∼ 91 (n = 389)

92 ∼ 98 (n = 231)

>98 (n = 205)

Age (years)

73.79 ± 5.02

74.86 ± 4.95

73.66 ± 5.05

73.42 ± 4.90

72.77 ± 4.95

<0.001

Male, n(%)

563(48.8)

141(43.0)

193(49.6)

123(53.2)

106(51.7)

0.070

Comorbidities, n(%)

      

 Diabetes, n(%)

144(12.5)

50(15.2)

48(12.3)

27(11.7)

19(9.3)

0.224

 Hypertension, n(%)

225(19.5)

84(25.6)

76(19.5)

32(13.9)

33(16.1)

0.003

 COPD, n(%)

114(9.9)

36(11.0)

37(9.5)

25(10.8)

16(7.8)

0.632

 CKD, n(%)

230(19.9)

80(24.4)

70(18.0)

49(21.2)

31(15.1)

0.042

 Cardiovascular Diseases, n(%)

172(14.9)

57(17.4)

50(12.9)

31(13.4)

34(16.6)

0.292

 Sepsis, n(%)

361(31.3)

117(35.7)

128(32.9)

58(25.1)

58(28.3)

0.039

Laboratory parameters

      

 WBC count (109/L)

10.10 ± 2.43

11.43 ± 2.94

9.87 ± 2.15

9.48 ± 1.82

9.11 ± 1.58

<0.001

 Hemoglobin (g/L)

99.87 ± 13.19

91.53 ± 9.68

98.54 ± 10.82

103.77 ± 10.62

111.33 ± 14.79

<0.001

 Creatinine (mg/dl)

1.40 ± 0.51

1.49 ± 0.62

1.45 ± 0.53

1.29 ± 0.44

1.27 ± 0.29

<0.001

Scoring

      

 SOFA

5.00[3.00 ∼ 7.00]

6.00(4.00 ∼ 8.00)

5.00(3.00 ∼ 7.00)

5.00(3.00 ∼ 7.00)

4.00(2.00 ∼ 5.00)

<0.001

 APACHE II

17.00[13.00 ∼ 20.00]

20.00(16.00 ∼ 24.00)

16.00(12.00 ∼ 19.00)

15.00(10.00 ∼ 19.00)

15.00(12.00 ∼ 19.00)

<0.001

Treatmentn, (%)

      

 RRT, n(%)

97(8.4)

43(13.1)

28(7.2)

16(6.9)

10(4.9)

0.003

 Vasopressor, n(%)

483(41.9)

162(49.4)

144(37.0)

97(42.0)

80(39.0)

0.007

Primary outcomes

      

 Mortality within 30 days post-extubation, n(%)

166(14.4)

62(18.9)

48(12.3)

33(14.3)

23(11.2)

0.038

 Pneumonia within 30 days post-extubation, n(%)

139(12.1)

51(15.5)

50(12.9)

25(10.8)

13(6.3)

0.014

 Reintubation within 72 h, n(%)

103(8.9)

46(14.0)

28(7.2)

14(6.1)

15(7.3)

0.002

 Dysphagia, n(%)

99(8.6)

40(12.2)

38(9.8)

12(5.2)

9(4.4)

0.003

Secondary outcomes

      

 LOS in ICU (days)

8.00[6.00 ∼ 10.00]

10.00(7.00 ∼ 12.00)

8.00(6.00 ∼ 9.00)

7.00(5.00 ∼ 9.00)

6.00(5.00 ∼ 8.00)

<0.001

 LOS in hospital (days)

21.00[17.00 ∼ 26.00]

25.00(20.00 ∼ 30.00)

22.00(16.00 ∼ 26.00)

19.00(16.00 ∼ 24.00)

17.00(14.00 ∼ 20.00)

<0.001

  1. Continuous variables are presented as mean ± standard deviation or median (interquartile) with number (proportion, %) for categorical variables. P values among groups are calculated by one-way ANOVA or Kruskal-Wallis H tests for continuous variables, Chi-square test for categorical variables. Abbreviations: GNRI, geriatric nutritional risk index; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; WBC, white blood cell; SOFA, Sequential Organ Failure Assessment; APACHE, Acute Physiologic and Chronic Health Evaluation; RRT, renal replacement therapy; LOS, length of stay