The importance of uric acid levels in geriatric patients with respiratory failure under noninvasive mechanical ventilation in the respiratory intensive care unit

Yıldız, Murat; Çelik, Deniz; Özdemir, Tarkan; Doğanay, Güler Eraslan; Doğanci, Melek; Cırık, Mustafa Özgür; Arı, Maşide; Ensarioğlu, Kerem; Cifci, Ayşe; Kızılgöz, Derya

doi:10.1186/s12890-025-03603-2

Table 4 Correlation analysis of parameters for intensive care unit scores, NIMV requirement and outcome for patients above 65 years old

From: The importance of uric acid levels in geriatric patients with respiratory failure under noninvasive mechanical ventilation in the respiratory intensive care unit

Parameters		Geriatric Patients (> 65 years)
Parameters		Glasgow Coma	APACHE II	SOFA Score	NIMV Requirement	Outcome	Mortality
Uric Acid	CC	-0.050	0.164^**	0.266^**	0.125^**	-0.049	-0.003
Uric Acid	P value	0.183	0.001	0.001	0.002	0.090	0.929
Hospitalization Duration	CC	0.029	-0.019	-0.023	0.028	-0.159^**	0.009
Hospitalization Duration	P value	0.430	0.600	0.534	0.456	0.001	0.814
Chronic Obstructive Pulmonary Disease	CC	0.045	-0.098^**	-0.114^**	0.353^**	-0.259^**	-0.167^**
Chronic Obstructive Pulmonary Disease	P value	0.217	0.007	0.002	0.001	0.001	0.000
Pneumonia	CC	-0.100^**	0.070	0.020	-0.282^**	0.203^**	0.097^**
Pneumonia	P value	0.006	0.054	0.590	0.001	0.001	0.008
Diabetes Mellitus	CC	-0.005	-0.016	-0.024	0.001	-0.011	0.023
Diabetes Mellitus	P value	0.882	0.664	0.512	0.995	0.744	0.530
Interstitial Lung Disease	CC	0.044	-0.018	0.003	-0.148^**	0.138^**	0.105^**
Interstitial Lung Disease	P value	0.231	0.621	0.925	0.001	0.001	0.004
Lung Malignancy	CC	-0.083^*	0.078^*	0.114^**	-0.051	0.123^**	0.069
Lung Malignancy	P value	0.023	0.034	0.002	0.161	0.001	0.058
Pulmonary Thromboembolism	CC	0.039	-0.025	-0.031	-0.175^**	-0.060	-0.013
Pulmonary Thromboembolism	P value	0.288	0.502	0.392	0.001	0.080	0.717
Congestive Heart Failure	CC	-0.043	-0.020	0.071	-0.024	-0.025	-0.042
Congestive Heart Failure	P value	0.242	0.592	0.051	0.511	0.467	0.253
Atrial Fibrillation	CC	0.032	-0.055	-0.022	0.020	-0.073^*	-0.021
Atrial Fibrillation	P value	0.385	0.130	0.539	0.589	0.034	0.561
Bronchiectasis	CC	-0.019	-0.047	-0.069	0.002	0.010	-0.033
Bronchiectasis	P value	0.598	0.196	0.059	0.962	0.765	0.368
Creatinine	CC	-0.015	0.276^**	0.365^**	-0.006	-0.041	0.011
Creatinine	P value	0.688	0.001	0.001	0.871	0.154	0.768
Blood Urea Nitrogen	CC	-0.032	0.217^**	0.335^**	-0.012	0.016	0.062
Blood Urea Nitrogen	P value	0.391	0.001	0.001	0.754	0.590	0.099
Glomerular Filtration Rate	CC	0.086^*	-0.278^**	-0.402^**	0.010	0.006	-0.008
Glomerular Filtration Rate	P value	0.019	0.001	0.001	0.789	0.831	0.816
Sodium	CC	-0.099^**	-0.056	0.064	0.138^**	-0.014	-0.006
Sodium	P value	0.007	0.128	0.082	0.001	0.623	0.862
Potassium	CC	0.133^**	-0.029	-0.025	0.133^**	-0.140^**	-0.125^**
Potassium	P value	0.001	0.429	0.486	0.001	0.001	0.001
Calcium	CC	0.083^*	-0.072	-0.151^**	0.108^**	-0.128^**	-0.099^**
Calcium	P value	0.025	0.052	0.001	0.003	0.001	0.007
Chloride	CC	-0.035	0.119^**	0.153^**	-0.243^**	0.082^**	0.008
Chloride	P value	0.339	0.001	0.001	0.001	0.005	0.829
Magnesium	CC	0.045	0.050	0.041	-0.009	-0.039	-0.027
Magnesium	P value	0.244	0.192	0.293	0.805	0.208	0.484
Albumin	CC	0.123^**	-0.077^*	-0.158^**	0.215^**	-0.274^**	-0.230^**
Albumin	P value	0.002	0.035	0.001	0.001	0.001	0.000
pH	CC	-0.038	-0.090^*	-0.050	-0.438^**	0.095^**	0.090^*
pH	P value	0.303	0.015	0.170	0.001	0.002	0.013
Partial carbon dioxide	CC	0.057	-0.087^*	-0.072	0.629^**	-0.163^**	-0.084^*
Partial carbon dioxide	P value	0.119	0.017	0.051	0.001	0.001	0.022
Bicarbonate	CC	0.047	-0.167^**	-0.175^**	0.409^**	-0.108^**	-0.013
Bicarbonate	P value	0.197	0.001	0.001	0.001	0.001	0.725

CC: Correlation coefficient; SD: Standard Deviation; SOFA: Sequential Organ Failure Assessment; NIMV: Non-Invasive Mechanical Ventilation. For outcome comparison, Kendall’s Tau B association was utilized, while the remaining comparison was made by Spearman’s correlation

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