Table 3 Prognostic impact, HRCT findings, and IPF diagnostic criteria
Parameter | Clinical Value | Diagnostic Criteria | Differential Features from Other ILDs |
|---|---|---|---|
Mortality Rate | 20.9% (18/86) | - | - |
Definite UIP Pattern | Count: 42 (48.8%) Mean GAP: 3.95 Median: 4.0 SD: 1.85 | - Basal and peripheral distribution - Honeycombing - Reticulation - Traction bronchiectasis | - Absence of upper lobe predominance - Absence of extensive ground glass - Absence of micronodules - Absence of cysts |
Probable UIP Pattern | Count: 38 (44.2%) Mean GAP: 4.05 Median: 4.0 SD: 1.77 | - Basal and peripheral distribution - Reticulation - Traction bronchiectasis - Without honeycombing | - Absence of consolidation - Absence of non-subpleural nodules - Absence of air trapping |
Indeterminate Pattern | Count: 6 (7.0%) Mean GAP: 3.83 Median: 4.0 SD: 1.83 | - Atypical distribution pattern - Mild reticulation - Inconclusive fibrosis findings | - Absence of extensive mosaic perfusion - Absence of peribronchovascular distribution |
Comorbidity Rate | 69.3% (61/86) | - | - |
Mean FVC | 72.59% ± 21.39% | Restrictive pattern on PFTs | Differentiation from obstructive patterns |
Mean DLCO | 53.31% ± 17.43% | Reduced DLCO with preserved KCO | Disproportionate DLCO reduction in PH |
GAP Index | Mean: 3.99 ± 1.80 Range: 0.0–8.0 | Core Diagnostic Requirements: - Age > 60 years - Dyspnea > 6 months - Bilateral basal crackles - Restrictive pattern | Exclusion Criteria: - Known causes of ILD - Collagen tissue disease - Drug/environmental exposure - Occupational exposure |