Table 5 Multivariate Cox regression analysis for mortality
Variable | Hazard Ratio (95% CI) | p-value | Adjusted HR* (95% CI) | Adjusted p-value |
|---|---|---|---|---|
GAP Index | ||||
- Per unit increase | 1.69 (1.22–2.34) | 0.0016 | 1.58 (1.14–2.19) | 0.006 |
Smoking Status | ||||
- Never (reference) | 1.00 | - | 1.00 | - |
- Active | 1.87 (1.15–3.04) | 0.012 | 1.76 (1.08–2.87) | 0.023 |
- Former | 1.45 (0.88–2.39) | 0.147 | 1.38 (0.83–2.29) | 0.216 |
Comorbidities | ||||
- No (reference) | 1.00 | - | 1.00 | - |
- Yes | 1.53 (1.12–2.09) | 0.008 | 1.47 (1.07–2.02) | 0.018 |
Age | ||||
- Per year increase | 1.04 (1.01–1.07) | 0.023 | 1.03 (1.00-1.06) | 0.047 |
Gender | ||||
- Female (reference) | 1.00 | - | 1.00 | - |
- Male | 1.42 (0.98–2.06) | 0.064 | 1.38 (0.95–2.01) | 0.092 |
FVC/DLCO ratio | ||||
- ≤1.6 (reference) | 1.00 | - | 1.00 | - |
- >1.6 | 1.89 (1.24–2.88) | 0.003 | 1.82 (1.19–2.79) | 0.006 |