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Table 1 Demographic data, spirometric variables, and values for FENO and peripheral eosinophils of patients with positive or negative bronchial provocation tests

From: Airway inflammation, bronchial hyperresponsiveness, and anti-asthma therapy responses in cough variant asthma and classic asthma with FEV1% ≥80% predicted

Variables

CA patients

CVA patients

P values

n

202

278

-

Male, n (%)

79 (39.1%)

83 (29.86%)

0.058

Age, years

44.0 (21.25)

47.0 (22.0)

0.249

Height, m

1.61 (0.146)

1.61 (0.12)

0.324

Weight, kg

60.0 (17)

58.5 (15)

0.272

BMI, kg/m2

23.13 (4.88)

22.77 (3.99)

0.544

Past smoking history (n / %) *

31 (15.35%)

39 (14.03%)

0.6863

Allergic rhinitis (n / %)

60 (29.70%)

67 (24.10%)

0.1695

FVC, % predicted

101.9 (15.63)

101.7 (16.12)

0.803

FEV1, % predicted

97.85 (14.83)

97.6 (15.12)

0.786

FEV1/FVC, %

79.83 (8.53)

80.63 (9.08)

0.049

PEF, % predicted

100 (17.19)

101.2 (15.59)

0.276

MEF75, % predicted

94.1 (17.52)

94.51 (17.4)

0.653

MEF50, % predicted

72.4 (23.42)

72.95 (25.15)

0.751

MEF25, % predicted

58.05 (27.52)

58.40 (29.58)

0.555

MMEF, % predicted

66.63 (22.25)

68.35 (25.48)

0.698

SAD, n (%)

93 (46.04%)

111 (39.93%)

0.1812

FENO, ppb

36.0 (58)

24.0 (30.25)

< 0.0001

WBC, ×10^9/L §

6.6 (2.207)

6.5 (2.5)

0.775

EOS in blood, cells/µl §

0.185 (0.26)

0.13 (0.2)

0.065

EOS in blood, % §

2.85 (3.575)

2.3 (3.0)

0.131

PD20, mg

0.7165 (0.9409)

0.7927 (1.18)

0.231

  1. BMI, Body mass index; FVC, Forced vital capacity; FEV1, Forced expiratory volume in 1 s; PEF, Feak expiratory flow; MEF25, Forced expiratory flow at 75% of FVC; MEF50, Forced expiratory flow at 50% of FVC; MEF75, Forced expiratory flow at 25% of FVC; MMEF, Forced expiratory flow at 25–75% of FVC; %pred, actual measured value of spirometric indices as a percentage of predicted value; FENO, Fractional exhaled nitric oxide; ppb, parts per billion; EOS, Eosinophils; PD20, Provocative dose causing a 20% fall in FEV in the first second
  2. SAD was identified if 2 of the variables MEF50%, MEF25% and MMEF were lower than 65%
  3. Median (IQR) values for all
  4. * < 10 pack-year smoking history
  5. §n = 138 for CA group and n = 171 for CVA group
  6. Bold font indicates statistical significance