Skip to main content

Table 1 Baseline characteristics of the patients examined, grouped based on randomized treatment

From: Comparison of ICS dose reduction vs. montelukast discontinuation for step-down therapy in well-controlled asthma: a pilot randomized controlled trial

Parameter

Group Montelukast (n = 37)

Group ICS (n = 34)

P-Value

Age (years), (mean ± SD)

41.8 ± 13.08

39.1 ± 12.14

0.39

Gender (Female %)

75%

68%

0.57

Marital Status (Married)

68%

78%

0.67

Weight (Kg), (mean ± SD)

71.6 ± 13.99

70.8 ± 14.69

0.81

Height (m), (mean ± SD)

1.65 ± 0.86

1.64 ± 0.11

0.93

Body Mass Index (mean ± SD)

26.3 ± 4.44

25.3 ± 6.6

 

Years from asthma diagnosis (mean ± SD)

8.8 ± 6.22

8.17 ± 6.44

0.48*

Allergic conditions

30%

44%

0.20

Gastroesophageal reflux disease

27%

27%

0.99

Diabetes mellitus

2.5%

6%

0.37

Hypertension

2.5%

10%

0.16

ACT score

22.7 ± 1.92

22.45 ± 2.64

0.14*

Daytime-CCS

1.23 ± 1.33

1.34 ± 1.28

0.50*

Night time-CCS

1.35 ± 0.73

1.50 ± 1.14

0.16*

Pre-FVC (% predicted)

79.36 ± 13.26

84.76 ± 17.48

0.17

Pre-FEV1 (% predicted)

70.62 ± 16.69

73.28 ± 15.08

0.53

FEV1/FVC (Pre)

81.19 ± 14.84

75.47 ± 10.19

0.10

  1. Group Montelukast: Half dose of their ICS + montelukast
  2. Group ICS: Full dose of their ICS without montelukast
  3. Allergic conditions includes hives, allergic rhinitis, and/or allergic skin conditions
  4. Abbreviations: ACT score = Asthma Control Test score, FVC = Forced vital capacity, CCS = Cough symptom score, Pre-FEV1 = Pre bronchodilator forced expiratory volume in 1 s
  5. *Mann-Whitney U Test