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Table 2 Top differentially methylated positions associated with former and current cannabis smoking

From: Cannabis smoking is associated with persistent epigenome-wide disruptions despite smoking cessation

CpG

Beta difference

FDR

Chr

Relation to CpG Island

Gene symbol

Cannabis smoking group

cg14190196

0.012

7.32 × 10–56

9

North Shelf

WDR31

Former

cg24960778

− 0.031

1.45 × 10–32

2

Open Sea

No annotation

Former

cg08949296

− 0.002

4.17 × 10–29

8

Island

GDAP;JPH1

Former

cg08670281

− 0.097

6.28 × 10–29

19

South Shore

CYP4 F11

Former

cg07305270

0.007

7.03 × 10–27

1

Open Sea

No annotation

Former

cg19558972

0.160

1.79 × 10–77

22

Open Sea

IGLL1

Current

cg08222002

0.013

3.65 × 10–34

10

South Shore

JMJD1 C

Current

cg07502389

− 0.027

6.52 × 10–26

8

Island

NEFM

Current

cg26538214

0.001

7.58 × 10–23

10

Island

KLF6

Current

cg07413747

− 0.078

1.61 × 10–22

10

Open Sea

PLXDC2

Current

  1. Abbreviations: CpG Cytosine-guanine residue, FDR false discovery rate