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Table 3 Impact of different treatment approaches on key respiratory indicators across groups

From: Effect of home noninvasive positive pressure ventilation combined with pulmonary rehabilitation on dyspnea severity and quality of life in patients with severe stable chronic obstructive pulmonary disease combined with chronic type II respiratory failure: a randomized controlled trial

Indicator

Group

Pre-Treatment Mean ± SD

Post-Treatment Mean ± SD

Change Mean ± SD

Within-group difference (p-value)

FEV1%

CTG

0.6513 ± 0.2678

0.6913 ± 0.1395

0.04 ± 0.155

0.035

 

CPRNG

0.6594 ± 0.2119

0.7642 ± 0.1947

0.10 ± 0.08

 < 0.001

 

Inter-group difference (p-value)

0.871

0.014

0.008

 

FEV1 (L)

CTG

1.12 ± 0.34

1.16 ± 0.32

0.04 ± 0.10

0.745

 

CPRNG

1.10 ± 0.30

1.26 ± 0.35

0.16 ± 0.12

 < 0.001

 

Inter-group difference (p-value)

0.165

 < 0.001

 < 0.001

 

FVC (L)

CTG

2.90 ± 0.90

3.05 ± 0.85

0.15 ± 0.12

0.043

 

CPRNG

2.92 ± 0.75

3.40 ± 0.80

0.48 ± 0.18

 < 0.001

 

Inter-group difference (p-value)

0.612

 < 0.001

 < 0.001

 

FEV1/FVC ratio

CTG

0.38 ± 0.09

0.38 ± 0.07

0.00 ± 0.06

0.057

 

CPRNG

0.35 ± 0.08

0.43 ± 0.09

0.12 ± 0.07

 < 0.001

 

Inter-group difference (p-value)

 

 < 0.001

 < 0.001

 

6MWT

CTG

268.7 ± 21.13

278.7 ± 19.36

10.0 ± 11.06

0.012

 

CPRNG

274.2 ± 19.96

288.7 ± 19.62

14.52 ± 7.676

 < 0.001

 

Inter-group difference (p-value)

0.645

0.008

0.001

 

Mean PAP (mmHg)

CTG

36.50 ± 9.398

34.50 ± 9.10

− 2.00 ± 2.543

0.23

 

CPRNG

37.23 ± 8.659

34.97 ± 7.627

− 2.25 ± 2.476

0.015

 

Inter-group difference (p-value)

0.742

0.038

0.023

 

PaO₂ (mmHg)

CTG

57.78 ± 6.079

62.00 ± 4.473

4.22 ± 3.375

0.059

 

CPRNG

55.72 ± 4.767

66.32 ± 3.709

10.60 ± 2.932

 < 0.001

 

Inter-group difference (p-value)

0.538

0.001

 < 0.001

 

PaCO₂ (mmHg)

CTG

53.30 ± 4.289

51.00 ± 5.935

− 2.30 ± 6.258

0.001

 

CPRNG

61.85 ± 6.981

50.45 ± 1.690

− 11.39 ± 5.787

 < 0.001

 

Inter-group difference (p-value)

0.053

0.003

0.002

 
  1. FEV1% Forced Expiratory Volume in 1 s percentage, 6MWT 6-Minute Walk Test, Mean PAP (mmHg) Mean Pulmonary Artery Pressure (in mmHg), PaO₂ (mmHg) Partial Pressure of Oxygen (in mmHg), PaCO₂ (mmHg) Partial Pressure of Carbon Dioxide (in mmHg)