Parameters | Control | Pure HLP | PTB | T2DM | T2DM + PTB | Statistical value | P value | |||
---|---|---|---|---|---|---|---|---|---|---|
HLP (-) | HLP (+) | HLP (-) | HLP (+) | HLP (-) | HLP (+) | |||||
No. of cases | 40 | 60 | 40 | 60 | 40 | 60 | 40 | 60 | ||
Age, years (X ± S) | 40.8 ± 7.36 | 44.8 ± 8.51 | 46.1 ± 8.93 | 49.3 ± 10.72 | 54.59 ± 10.78 | 56.34 ± 11.52 | 52.89 ± 10.68 | 55.69 ± 9.78 | F = 16.04 | < 0.01 |
Sex | χ2 = 23.492 | < 0.01 | ||||||||
Men [n (%)] | 28 (46.6) | 36 (60) | 30 (75) | 45 (75) | 27 (67.5) | 48 (80) | 34 (85) | 39 (65) | ||
Women [n (%)] | 32 (53.3) | 24 (40) | 10 (25) | 15 (25) | 13 (32.5) | 12 (20) | 6 (15) | 21 (35) | ||
BMI (Kg/m2) | 21.41 ± 1.47 | 27.48 ± 2.21 | 20.98 ± 1.57 | 24.37 ± 2.37 | 22.57 ± 2.05 | 29.67 ± 2.48 1 | 23.75 ± 1.35 | 26.3 ± 3.28 | H = 257.61 | < 0.01 |
Insulin (μIU/mL) | 9.43 ± 2.23 2 | 11.48 ± 4.42 | 9.23 ± 2.2 | 10.05 ± 3.28 | 12.94 ± 6.38 | 14.43 ± 10.54 3 | 10.71 ± 3.93 | 12.63 ± 5.813 | H = 35.36 | < 0.01 |
HOMA-IR | 2.02 ± 0.46 | 2.68 ± 1.08 | 2.13 ± 0.5 | 2.5 ± 0.85 | 4.51 ± 2.67 | 5.86 ± 4.4 | 3.96 ± 2.06 | 5.11 ± 2.697 | H = 186.19 | < 0.01 |
HbA1c (%) | 5.25 ± 0.29 | 4.9 ± 0.55 | 5.32 ± 0.38 | 5.36 ± 0.41 | 7.38 ± 1.47 | 7.6 ± 1.793 | 7.92 ± 2.91 | 8.23 ± 3.583 | H = 261.75 | < 0.01 |
FSG (mmol/L) | 4.88 ± 0.53 2 | 5.29 ± 0.33 | 5.21 ± 0.46 | 5.59 ± 0.46 | 7.81 ± 1.81 | 9.27 ± 3.39 3 | 8.41 ± 2.78 | 9.36 ± 3.3 3 | H = 264.27 | < 0.01 |
TC (mmol/L) | 4.69 ± 0.62 2 | 6.44 ± 0.75 4 | 4.61 ± 0.69 | 5.97 ± 1.17 | 4.53 ± 0.66 | 6.21 ± 1.53 | 4.33 ± 0.75 | 5.69 ± 1.48 | H = 159.68 | < 0.01 |
LDL-C (mmol/L) | 2.99 ± 0.37 | 4.55 ± 0.53 5 | 3.09 ± 0.5 | 3.97 ± 0.93 | 3.08 ± 0.46 | 3.98 ± 1.03 | 2.91 ± 0.62 | 3.73 ± 1.12 | F = 28.49 | < 0.01 |
TG (mmol/L) | 1.14 ± 0.422 | 3.56 ± 2.29 6 | 1.13 ± 0.31 | 2.12 ± 1.03 | 1.21 ± 0.32 | 2.99 ± 2.32 | 1.15 ± 0.29 | 2.34 ± 1.5 | H = 191.32 | < 0.01 |
HDL-C (mmol/L) | 1.43 ± 0.27 | 1.48 ± 0.27 | 1.42 ± 0.31 | 1.5 ± 0.33 | 1.34 ± 0.26 | 1.42 ± 0.4 | 1.34 ± 0.36 | 1.35 ± 0.39 | F = 1.89 | > 0.05 |
ApoA I (g/L) | 1.49 ± 0.28 | 2.46 ± 0.24 | 1.49 ± 0.24 | 1.72 ± 0.38 | 1.76 ± 0.43 | 4.0 ± 1.06 7 | 1.55 ± 0.24 | 2.05 ± 0.38 | H = 141.83 | < 0.01 |
Apo B (g/L) | 0.79 ± 0.18 | 0.86 ± 0.31 | 0.78 ± 0.13 | 0.9 ± 0.24 | 1.02 ± 0.18 | 1.2 ± 0.61 7 | 0.92 ± 0.16 | 0.94 ± 0.22 | H = 105.54 | < 0.01 |
oxLDL(U/L) | 1180.95 ± 237.6 8 | 2465.45 ± 894.67 | 1632.3 ± 484.25 | 1987.25 ± 450.13 | 2086.6 ± 552,85 | 2932.43 ± 1216.45 | 1992.93 ± 386.47 | 2458.5 ± 1262.06 | H = 143.13 | < 0.01 |
oxHDL (μg/L) | 6.42 ± 3.22 | 14.88 ± 4.26 | 11.03 ± 3.87 | 14.48 ± 6.54 | 19.54 ± 6.52 | 28.47 ± 19.56 | 16.42 ± 6.24 | 23.48 ± 19.13 9 | H = 147.32 | < 0.01 |