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Table 1 Characteristics of participants in the NHANES

From: Impact of COPD and sarcopenia on all-cause and respiratory mortality in US adults: NHANES 1999–2018

Variable

Total

(n = 21961)

COPD-/SAR-

(n = 19072)

COPD-/SAR+

(n = 2381)

COPD+/SAR-

(n = 388)

COPD+/SAR+

(n = 120)

P value

Age (years)

42.21(0.19)

41.17(0.20)

50.63(0.42)

54.00(0.63)

60.32(1.37)

< 0.0001

Sex, n (%)

     

< 0.001

 Female

10,777(49.81)

9399(49.91)

1112(45.82)

215(62.78)

51(43.65)

 

 Male

11,184(50.19)

9673(50.09)

1269(54.18)

173(37.22)

69(56.35)

 

BMI (kg/m2)

28.00(0.08)

27.55(0.07)

32.92(0.18)

28.02(0.45)

33.78(0.97)

< 0.0001

Waist circumference (cm)

95.95(0.20)

94.85(0.20)

107.30(0.42)

99.12(1.09)

113.83(2.42)

< 0.0001

Ethnicity, n (%)

     

< 0.0001

 Mexican American

4239(8.75)

3195(7.90)

1014(21.22)

15(0.92)

15(2.96)

 

 Non-Hispanic Black

4354(10.35)

4171(11.09)

100(2.63)

74(7.65)

9(3.65)

 

 Non-Hispanic White

9627(68.08)

8424(68.49)

873(58.69)

251(82.25)

79(82.43)

 

 Other Hispanic

1529(6.16)

1296(5.91)

211(10.14)

11(2.14)

11(5.01)

 

 Other races (Including multiracial)

2212(6.67)

1986(6.61)

183(7.33)

37(7.05)

6(5.96)

 

Educational level, n (%)

     

< 0.0001

 Less than 9th grade

2280(4.90)

1558(4.00)

643(14.44)

50(7.71)

29(13.82)

 

 9-11th grade

3101(10.76)

2612(10.31)

392(13.92)

76(18.04)

21(16.19)

 

 High school graduate

5031(23.84)

4351(23.42)

569(29.03)

87(23.30)

24(24.83)

 

 College graduate or above

5043(28.52)

4693(29.94)

276(14.65)

62(20.51)

12(9.95)

 

 Some college or associate degree

6506(31.99)

5858(32.33)

501(27.96)

113(30.44)

34(35.20)

 

Family income, n (%)

     

< 0.0001

 High

7273(43.47)

6647(44.88)

496(29.41)

105(37.49)

25(23.39)

 

 Medium

8198(35.13)

7075(34.72)

944(40.20)

134(33.78)

45(38.93)

 

 Low

6490(21.40)

5350(20.41)

941(30.39)

149(28.73)

50(37.68)

 

Marital status, n (%)

     

< 0.0001

 Living with partner

1860(8.57)

1699(8.85)

137(6.26)

22(6.18)

2(2.79)

 

 Married

11,593(55.44)

9903(55.03)

1438(60.54)

190(56.63)

62(48.91)

 

 Never married

4625(20.81)

4293(21.67)

281(14.27)

38(7.06)

13(13.26)

 

 Other

3883(15.18)

3177(14.45)

525(18.93)

138(30.13)

43(35.05)

 

Alcohol user, n (%)

     

< 0.0001

 former

3232(12.28)

2528(11.21)

556(21.32)

109(22.91)

39(29.21)

 

 heavy

5040(24.49)

4490(24.90)

465(21.25)

70(20.29)

15(13.58)

 

 moderate

3568(18.36)

3274(18.98)

225(11.12)

58(19.88)

11(9.95)

 

 mild

7170(34.05)

6354(34.58)

652(28.58)

122(30.34)

42(35.64)

 

 never

2951(10.83)

2426(10.33)

483(17.74)

29(6.59)

13(11.62)

 

Smoking status, n (%)

     

< 0.0001

 former

4777(22.03)

3892(21.18)

669(26.64)

147(36.40)

69(53.77)

 

 never

12,060(53.86)

10,653(54.73)

1326(55.13)

64(17.33)

17(12.37)

 

 now

5124(24.11)

4527(24.10)

386(18.23)

177(46.27)

34(33.86)

 

Hemoglobin (g/L)

14.45(0.02)

14.45(0.02)

14.46(0.05)

14.29(0.11)

14.35(0.22)

0.43

Total bilirubin (mmol/L)

11.46(0.08)

11.53(0.08)

10.76(0.17)

10.73(0.47)

10.87(0.69)

< 0.0001

Triglycerides (mmol/L)

1.66(0.02)

1.62(0.02)

2.00(0.05)

2.02(0.20)

2.24(0.23)

< 0.0001

Total cholesterol (mmol/L)

5.09(0.01)

5.07(0.01)

5.25(0.03)

5.41(0.09)

5.29(0.14)

< 0.0001

HDL-cholesterol (mmol/L)

1.36(0.01)

1.37(0.01)

1.27(0.01)

1.44(0.03)

1.24(0.04)

< 0.0001

HbA1c (%)

5.47(0.01)

5.43(0.01)

5.85(0.03)

5.67(0.06)

6.00(0.09)

< 0.0001

UACR (mg/g)

5.93(4.03,10.33)

5.77(3.98, 9.91)

8.06(5.14,16.74)

7.16(4.46,13.21)

9.74(4.92,25.45)

< 0.0001

eGFR (mL/min/1.73 m²)

99.25(85.24, 111.82)

99.71(85.86, 111.94)

97.93(81.53, 112.60)

88.98(75.77, 101.03)

88.07(73.23, 97.38)

< 0.0001

CVD

     

< 0.0001

 no

20,362(94.61)

17,980(95.82)

2022(85.88)

288(78.30)

72(66.90)

 

 yes

1599(5.39)

1092(4.18)

359(14.12)

100(21.70)

48(33.10)

 

DM

     

< 0.0001

 no

19,331(91.37)

17,140(92.65)

1786(78.63)

328(87.89)

77(63.60)

 

 yes

2630(8.63)

1932(7.35)

595(21.37)

60(12.11)

43(36.40)

 

Hypertension

     

< 0.0001

 no

14,451(69.95)

13,091(72.17)

1167(51.57)

161(47.99)

32(27.33)

 

 yes

7510(30.05)

5981(27.83)

1214(48.43)

227(52.01)

88(72.67)

 

Follow-up time (month)

135.00(64.00,201.00)

156.00(65.00,203.00)

105.00(60.00,189.00)

99.00(63.00,179.00)

91.00(45.00,142.00)

< 0.0001

  1. Abbreviations: COPD, Chronic Obstructive Pulmonary Disease; SAR, sarcopenia; BMI, body mass index; UACR, urinary albumin creatinine ratio; eGFR, estimated glomerular filtration rate
  2. Categorical variables are expressed as frequencies with weighted percentages, and continuous variables are expressed as weighted mean with standard error, or median with interquartile range
  3. Values in bold are statistically significant