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Table 2 Association of COPD/SAR with all-cause and respiratory mortality using the FNIH criteria

From: Impact of COPD and sarcopenia on all-cause and respiratory mortality in US adults: NHANES 1999–2018

Character

Crude model

Model 1

Model 2

Model 3

HR (95%CI)

P

HR (95%CI)

P

HR (95%CI)

P

HR (95%CI)

P

All-cause mortality

        

COPD-/SAR-

1 (ref)

 

1 (ref)

 

1 (ref)

 

1 (ref)

 

COPD-/SAR+

3.48(3.12, 3.89)

< 0.0001

1.39(1.25, 1.55)

< 0.0001

1.34(1.21, 1.48)

< 0.0001

1.33(1.20, 1.48)

< 0.0001

COPD+/SAR-

4.47(3.57, 5.60)

< 0.0001

2.27(1.81, 2.84)

< 0.0001

1.94(1.57, 2.38)

< 0.0001

1.51(1.21, 1.88)

< 0.001

COPD+/SAR+

9.28(6.33, 13.60)

< 0.0001

2.62(1.92, 3.57)

< 0.0001

2.24(1.64, 3.07)

< 0.0001

1.87(1.32, 2.66)

< 0.001

p for trend

 

< 0.0001

 

< 0.0001

 

< 0.0001

 

< 0.0001

Respiratory mortality

        

COPD-/SAR-

1 (ref)

 

1 (ref)

 

1 (ref)

 

1 (ref)

 

COPD-/SAR+

4.38(2.76, 6.95)

< 0.0001

1.39(0.86, 2.27)

0.18

1.26(0.74, 2.13)

0.39

1.82(0.91, 3.63)

0.09

COPD+/SAR-

33.61(21.68, 52.12)

< 0.0001

12.12(7.25, 20.25)

< 0.0001

9.54(5.66,16.08)

< 0.0001

5.16(2.96, 9.01)

< 0.0001

COPD+/SAR+

74.51(38.40, 144.57)

< 0.0001

12.37(6.36, 24.06)

< 0.0001

10.95(5.38,22.28)

< 0.0001

8.69(3.95, 19.14)

< 0.0001

p for trend

 

< 0.0001

 

< 0.0001

 

< 0.0001

 

< 0.0001

  1. Abbreviations: HR, hazard ratio; CI, confidence interval
  2. Crude model
  3. Model 1: Age, sex
  4. Model 2: Age, sex, ethnicity, marital, family income, educational level
  5. Model 3: Age, sex, ethnicity, marital, family income, educational level, BMI, waist circumference, hemoglobin, TG, total cholesterol, HDL, Total bilirubin, HbA1c, smoke, UACR, eGFR, alcohol use