Predictive value of neutrophil-lymphocyte ratio for all-cause mortality in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis

Table 1 Included studies

Study	Year	Country	Study design	Population	Patients (n)	Gender		Follow -up	NLR threshold
Study	Year	Country	Study design	Population	Patients (n)	Male	Female	Follow -up	NLR threshold
Aksoy et al. [29]	2018	Süreyyapaşa	Retro	AECOPD	2727	1867	860	28d	15
Alkhayat et al. [30]	2021	Egypt	pro	COPD	38	38	0	2Y	1.3
Ardestani et al. [31]	2021	Iran	Retro	AECOPD	829	555	274	NA	6.9
Duman et al. [32]	2015	Japan	Retro	COPD	1704	146	1558	6 M	7
Dwedar et al. [24]	2018	Egypt	pro	AECOPD	50	38	12	NA	6.24
Feng et al. [33]>	2023	China	Retro	AECOPD	503	489	14	90d	14.17
Galani et al. [34]	2021	Greece	Retro	AECOPD	127	86	41	28d	NA
Gayaf et al. [35]	2021	Turkey	pro	COPD	141	115	26	90d	NA
Gómez-Rosero et al. [36]	2021	Colombia	Retro	COPD	619	319	300	NA	5
Hu et al. [37]	2023	US	Retro	COPD	1715	966	749	NA	8.13
Karkra et al. [38]	2023	India	Retro	AECOPD	500	436	64	NA	14.83
Kumar et al. [39]	2017	Australia	Retro	AECOPD	181	88	93	90d	NA
Liu et al. [25]	2019	China	Retro	AECOPD	622	305	317	3 M	4.19
Luo et al. [40]	2021	China	Retro	AECOPD	533	355	178	28d	6.74
Peng et al. [41]	2022	China	Retro	AECOPD	494	248	246	30d	NA
Shao et al. [42]	2023	China	Retro	AECOPD	4235	3137	1098	1y	4.43
Sunnetcioglu, et al. [43]	2022	Turkey	Retro	COPD	134	83	51	30d	NA
Xiong et al. [44]	2017	China	Retro	COPD	368	116	252	24 M	3.3
Yao et al. [45]	2017	China	Retro	AECOPD	303	200	103	15d	6.24
Yao et al. [46]	2021	China	Retro	AECOPD	146	109	37	28d	16.83
Yu et al. [47]	2020	China	Retro	AECOPD	695	576	119	NA	NA
Fayiad et al. [48]	2024	Egypt	Retro	COPD	80	79	1	NA	NA
Liao et al. [49]	2024	China	Retro	AECOPD	619	516	103	NA	NA
Liu et al. [50]	2025	US	Retro	COPD	1234	677	577	24 h	NA

ISSN: 1471-2466