Table 2 Association between LC9 scores and respiratory symptoms (weighted)
From: Association between life’s crucial 9 and lung health: a population-based study
OR/β (95%CI), P value | |||
|---|---|---|---|
Crude model (Model 1) | Minimally adjusted model (Model 2) | Fully adjusted model (Model 3) | |
Outcome: cough | |||
LC9 score/10 | 0.62 (0.59, 0.66), < 0.0001 | 0.63 (0.59, 0.67), < 0.0001 | 0.72 (0.67, 0.77), < 0.0001 |
Low | Reference | Reference | Reference |
Moderate | 0.40 (0.34, 0.48), < 0.0001 | 0.44 (0.36, 0.53), < 0.0001 | 0.61 (0.50, 0.76), < 0.0001 |
High | 0.10 (0.07, 0.14), < 0.0001 | 0.11 (0.07, 0.15), < 0.0001 | 0.19 (0.13, 0.29), < 0.0001 |
P for trend | < 0.0001 | < 0.0001 | < 0.0001 |
Health behaviors score/10 | 0.72 (0.69, 0.75), < 0.0001 | 0.72 (0.69, 0.76), < 0.0001 | 0.80 (0.76, 0.85), < 0.0001 |
Health factors score/10 | 0.83 (0.79, 0.87), < 0.0001 | 0.82 (0.78, 0.86), < 0.0001 | 0.90 (0.85, 0.95), 0.0007 |
Outcome: phlegm | |||
LC9 score/10 | 0.65 (0.62, 0.70), < 0.0001 | 0.67 (0.63, 0.71), < 0.0001 | 0.71 (0.66, 0.76), < 0.0001 |
Low | Reference | Reference | Reference |
Moderate | 0.43 (0.35, 0.42), < 0.0001 | 0.47 (0.38, 0.58), < 0.0001 | 0.55 (0.44, 0.69), < 0.0001 |
High | 0.14 (0.10, 0.21), < 0.0001 | 0.16 (0.11, 0.23), < 0.0001 | 0.23 (0.16, 0.34), < 0.0001 |
P for trend | < 0.0001 | < 0.0001 | < 0.0001 |
Health behaviors score/10 | 0.74 (0.71, 0.78), < 0.0001 | 0.75 (0.72, 0.79), < 0.0001 | 0.79 (0.75, 0.84), < 0.0001 |
Health factors score/10 | 0.84 (0.80, 0.88), < 0.0001 | 0.84 (0.80, 0.88), < 0.0001 | 0.91 (0.86, 0.96), 0.0017 |
Outcome: wheeze | |||
LC9 score/10 | 0.65 (0.62, 0.68), < 0.0001 | 0.68 (0.65, 0.72), < 0.0001 | 0.72 (0.68, 0.76), < 0.0001 |
Low | Reference | Reference | Reference |
Moderate | 0.37 (0.32, 0.43), < 0.0001 | 0.43 (0.37, 0.51), < 0.0001 | 0.52 (0.44, 0.61), < 0.0001 |
High | 0.16 (0.12, 0.21), < 0.0001 | 0.21 (0.16, 0.28), < 0.0001 | 0.27 (0.20, 0.37), < 0.0001 |
P for trend | < 0.0001 | < 0.0001 | < 0.0001 |
Health behaviors score/10 | 0.78 (0.75, 0.80), < 0.0001 | 0.80 (0.78, 0.83), < 0.0001 | 0.85 (0.82, 0.89), < 0.0001 |
Health factors score/10 | 0.78 (0.75, 0.82), < 0.0001 | 0.81 (0.78, 0.85), < 0.0001 | 0.84 (0.80, 0.89), < 0.0001 |
Outcome: asthma | |||
LC9 score/10 | 0.81 (0.75, 0.87), < 0.0001 | 0.84 (0.78, 0.91), < 0.0001 | 0.83 (0.77, 0.89), < 0.0001 |
Low | Reference | Reference | Reference |
Moderate | 0.52 (0.43, 0.63), < 0.0001 | 0.60 (0.49, 0.74), < 0.0001 | 0.61 (0.49, 0.74), < 0.0001 |
High | 0.48 (0.33, 0.70), 0.0003 | 0.61 (0.40, 0.91), 0.0200 | 0.58 (0.38, 0.87), 0.0123 |
P for trend | 0.0004 | 0.0200 | 0.0123 |
Health behaviors score/10 | 0.90 (0.87, 0.94), < 0.0001 | 0.93 (0.89, 0.97), 0.0021 | 0.94 (0.90, 0.98), 0.0077 |
Health factors score/10 | 0.85 (0.80, 0.91), < 0.0001 | 0.87 (0.81, 0.93), 0.0002 | 0.87 (0.82, 0.94), 0.0003 |
Outcome: emphysema | |||
LC9 score/10 | 0.57 (0.53, 0.61), < 0.0001 | 0.59 (0.54, 0.65), < 0.0001 | 0.62 (0.55, 0.70), < 0.0001 |
Low | Reference | Reference | Reference |
Moderate | 0.31 (0.23, 0.40), < 0.0001 | 0.36 (0.25, 0.50), < 0.0001 | 0.41 (0.27, 0.61), 0.0001 |
High | 0.05 (0.02, 0.13), < 0.0001 | 0.08 (0.03, 0.21), < 0.0001 | 0.10 (0.04, 0.27), < 0.0001 |
P for trend | < 0.0001 | < 0.0001 | < 0.0001 |
Health behaviors score/10 | 0.64 (0.61, 0.68), < 0.0001 | 0.63 (0.58, 0.68), < 0.0001 | 0.63 (0.58, 0.69), < 0.0001 |
Health factors score/10 | 0.83 (0.77, 0.90), < 0.0001 | 0.89 (0.81, 0.97), 0.0096 | 1.00 (0.90, 1.11), 0.9684 |
Outcome: chronic bronchitis | |||
LC9 score/10 | 0.71 (0.67, 0.76), < 0.0001 | 0.77 (0.71, 0.83), < 0.0001 | 0.77 (0.71, 0.82), < 0.0001 |
Low | Reference | Reference | Reference |
Moderate | 0.47 (0.38, 0.58), < 0.0001 | 0.58 (0.45, 0.74), 0.0001 | 0.61 (0.47, 0.78), 0.0004 |
High | 0.26 (0.17, 0.41), < 0.0001 | 0.39 (0.24, 0.62), 0.0002 | 0.39 (0.24, 0.62), 0.0003 |
P for trend | < 0.0001 | < 0.0001 | 0.0001 |
Health behaviors score/10 | 0.82 (0.79, 0.86), < 0.0001 | 0.86 (0.81, 0.90), < 0.0001 | 0.86 (0.81, 0.91), < 0.0001 |
Health factors score/10 | 0.82 (0.77, 0.88), < 0.0001 | 0.87 (0.82, 0.93), < 0.0001 | 0.90 (0.84, 0.96), 0.0020 |
Outcome: COPD | |||
LC9 score/10 | 0.85 (0.80, 0.91), < 0.0001 | 0.85 (0.79, 0.91), < 0.0001 | 0.85 (0.79, 0.91), < 0.0001 |
Low | Reference | Reference | Reference |
Moderate | 0.90 (0.65, 1.24), 0.5209 | 0.81 (0.58, 1.12), 0.2075 | 0.78 (0.57, 1.07), 0.1349 |
High | 0.30 (0.20, 0.46), < 0.0001 | 0.28 (0.18, 0.44), < 0.0001 | 0.26 (0.17, 0.40), < 0.0001 |
P for trend | < 0.0001 | < 0.0001 | < 0.0001 |
Health behaviors score/10 | 0.83 (0.79, 0.88), < 0.0001 | 0.80 (0.75, 0.84), < 0.0001 | 0.77 (0.72, 0.82), < 0.0001 |
Health factors score/10 | 1.04 (0.97, 1.11), 0.3029 | 1.09 (1.02, 1.17), 0.0154 | 1.16 (1.08, 1.25), 0.0006 |
Outcome: FEV1 | |||
LC9 score/10 | 100.13 (81.95, 118.31), < 0.0001 | 66.70 (52.97, 80.43), < 0.0001 | 53.02 (39.30, 66.75), < 0.0001 |
Low | Reference | Reference | Reference |
Moderate | 277.73 (187.98, 367.47), < 0.0001 | 139.87 (90.04, 189.71), < 0.0001 | 98.11 (45.25, 150.96), 0.0010 |
High | 460.31 (362.71, 557.90), < 0.0001 | 268.62 (200.63, 336.62), < 0.0001 | 202.26 (131.10, 273.43), < 0.0001 |
P for trend | < 0.0001 | < 0.0001 | < 0.0001 |
Health behaviors score/10 | 35.49 (24.68, 46.29), < 0.0001 | 37.79 (28.24, 47.34), < 0.0001 | 25.62 (16.31, 34.93), < 0.0001 |
Health factors score/10 | 98.81 (81.08, 116.54), < 0.0001 | 38.46 (23.06, 53.86), < 0.0001 | 26.75 (10.86, 42.63), 0.0025 |
Outcome: FVC | |||
LC9 score/10 | 117.43 (93.45, 141.41), < 0.0001 | 78.41 (60.56, 96.26), < 0.0001 | 71.83 (54.04, 89.62), < 0.0001 |
Low | Reference | Reference | Reference |
Moderate | 342.13 (222.25, 462.00), < 0.0001 | 156.69 (86.18,227.20), 0.0001 | 139.83 (71.13, 208.53), 0.0004 |
High | 539.98 (415.20, 664.76), < 0.0001 | 303.47 (219.68, 387.26), < 0.0001 | 267.40 (183.78, 351.01), < 0.0001 |
P for trend | < 0.0001 | < 0.0001 | < 0.0001 |
Health behaviors score/10 | 23.88 (9.42, 38.33), 0.0022 | 20.62 (8.63, 32.61), 0.0017 | 8.50 (-3.12, 20.13), 0.1619 |
Health factors score/10 | 142.77 (120.41, 165.13), < 0.0001 | 78.37 (61.57, 95.17), < 0.0001 | 71.98 (53.12, 90.83), < 0.0001 |
Outcome: FEV1/FVC | |||
LC9 score/10 | 0.0032 (0.0019, 0.0045), < 0.0001 | 0.0020 (0.0006, 0.0034), 0.0069 | 0.0009 (-0.0005, 0.0022), 0.2232 |
Low | Reference | Reference | Reference |
Moderate | 0.0069 (0.0003, 0.0135), 0.0447 | 0.0070 (0.0004, 0.0137), 0.0444 | 0.0027 (-0.0040, 0.0093), 0.4360 |
High | 0.0152 (0.0081, 0.0223), 0.0001 | 0.0111(0.0034, 0.0188), 0.0074 | 0.0056 (-0.0021, 0.0133) < 0.1657 |
P for trend | 0.0001 | 0.0075 | 0.1518 |
Health behaviors score/10 | 0.0048 (0.0038, 0.0058), < 0.0001 | 0.0057 (0.0047, 0.0067), < 0.0001 | 0.0056 (0.0046, 0.0066), < 0.0001 |
Health factors score/10 | -0.0024 (-0.0040, -0.0058),0.0046 | -0.0058 (-0.0075, -0.0041),<0.0001 | -0.0068 (-0.0086, -0.0051), < 0.0001 |