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Table 3 Adjusted and unadjusted treatment response stratified by the whole cohort, SARD, and non-SARD subgroups

From: Serum inflammatory markers as predictors of therapeutic response in non-idiopathic pulmonary fibrosis fibrotic interstitial lung disease: a retrospective cohort analysis

Outcomes

High inflammatory markers group

Low to normal inflammatory markers group

p-value

All treated patients

(N = 167), N (%); OR [95% CI]

58 (55.8%)

22 (34.9%)

0.011

OR 2.35 [1.23–4.48]

0.010

OR* 2.45 [1.24–4.83]

0.010

Treated patients with underlying SARDs (N = 96), N (%); OR [95% CI]

38 (61.2%)

16 (47%)

0.202

OR 1.78 [0.77–4.15]

0.181

OR* 2.05 [0.81–5.14]

0.125

Treated patients without underlying SARDs (N = 71), N (%); OR [95% CI]

20 (47.6%)

6 (20.7%)

0.026

OR 3.48 [1.18–10.3]

0.024

OR* 3.49 [1.14–10.71]

0.029

  1. *Adjusted odd ratio with age, sex, duration of treatment at response evaluation, and baseline FVC (%predicted)