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Table 6 Group comparison according to anxiety score between baseline and 12 months post-treatment

From: Unveiling the psychosocial impact of Elexacaftor/Tezacaftor/Ivacaftor therapy in Cystic Fibrosis patients

 

No anxiety (n=43)

Change to no anxiety (n=12)

Change to anxiety (n=14)

With anxiety (n=22)

p-value

Age

30.0 [17.0, 58.0]

34.0 [23.0, 61.0]

29.5 [18.0, 55.0]

27.0 [18.0, 48.0]

0.335

Sex [Male]

29 (67.4%)

5 (41.7%)

6 (42.9%)

9 (40.9%)

0.108

Heterozygous

24 (55.8%)

3 (25.0%)

9 (64.3%)

15 (68.2%)

0.094

BMI (kg/m2)

21.5 [16.2, 32.0]

22.8 [19.2, 26.7]

23.2 [18.3, 29.4]

21.3 [18.1, 25.3]

0.064

FEV1%

63.0 [29.0, 108]

66.5 [34.0, 105]

62.5 [42.0, 93.0]

66.5 [31.0, 114]

0.950

Comorbility

     

 Pancreatic insufficiency

37 (86.0%)

11 (91.7%)

10 (71.4%)

18 (81.8%)

0.495

 Hydrocarbon intolerance

20 (46.5%)

7 (58.3%)

5 (35.7%)

5 (22.7%)

0.155

 Hepatopathy

11 (25.6%)

4 (33.3%)

4 (28.6%)

3 (13.6%)

0.557

Isolations

     

 Pseudomonas aeruginosa

19 (44.2%)

3 (25.0%)

5 (35.7%)

8 (36.4%)

0.659

Treatments

     

 Previous Modulator

20 (46.5%)

7 (58.3%)

4 (28.6%)

7 (31.8%)

0.302