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Table 6 Descriptive analysis and concordance correlation coefficient of primary and secondary end-points between masterscreen and meair

From: The Reliability of a Novel Structured Testing Device for Single-breath Lung Carbon Monoxide Uptake: A Randomized Comparison Crossover Study

Variables

MasterScreen

MeAir

Absolute value of difference

Pc (95% CI)

Pc

Strength of agreement

Primary end - point

      

 DLCO (mL·min− 1·mmHg− 1)

5.527 ± 1.981

5.627 ± 2.030

0.100 ± 0.296

0.984–0.991

0.988

Substantial

Secondary end-points

      

 DLCO/VA (mL·min− 1·mmHg− 1·L)

1.235(0.990, 1.495)

1.400(1.090, 1.650)

N/A

0.915–0.949

0.934

Moderate

 VA (L)

4.450 ± 1.068

4.148 ± 1.077

0.302 ± 0.218

0.924–0.955

0.942

Moderate

 VI (L)

2.687 ± 0.785

2.786 ± 0.827

0.099 ± 0.180

0.957–0.976

0.968

Substantial

 tBH (s)

11.900(11.360,12.970)

11.435(11.120,12.030)

N/A

0.663–0.790

0.733

Poor

 VA/tBH (L·s− 1)

0.365 ± 0.100

0.354 ± 0.100

0.011 ± 0.023

0.957–0.976

0.968

Substantial

 FICO (%)

0.295(0.291,0.299)

0.298(0.296,0.300)

N/A

0.261–0.423

0.344

Poor

 FACO (%)

0.080 ± 0.018

0.085 ± 0.019

0.005 ± 0.007

0.856–0.918

0.891

Poor

 FICH4 (%)

0.301(0.297,0.305)

0.299(0.295,0.301)

N/A

0.225–0.405

0.318

Poor

 FACH4 (%)

0.162(0.136,0.181)

0.176(0.151,0.189)

N/A

0.794–0.879

0.842

Poor

 \(\:\frac{{F}_{\text{I}\text{C}\text{O}}}{{F}_{\text{A}\text{C}\text{O}}}\)

3.647(3.177,4.329)

3.488(3.062,4.160)

N/A

0.856–0.919

0.892

Poor

 \(\:\frac{{F}_{\text{A}\text{C}\text{H}4}}{{F}_{\text{I}\text{C}\text{H}4}}\)

0.540(0.467,0.598)

0.599(0.508,0.642)

N/A

0.791–0.873

0.837

Poor

 \(\:\frac{{F}_{\text{I}\text{C}\text{O}}}{{F}_{\text{A}\text{C}\text{O}}}\cdot\frac{{F}_{\text{A}\text{C}\text{H}4}}{{F}_{\text{I}\text{C}\text{H}4}}\)

1.896(1.721,2.165)

1.986(1.767,2.224)

N/A

0.921–0.956

0.941

Moderate

 \(\:\text{L}\text{n}\left(\frac{{F}_{\text{I}\text{C}\text{O}}}{{F}_{\text{A}\text{C}\text{O}}}\cdot\frac{{F}_{\text{A}\text{C}\text{H}4}}{{F}_{\text{I}\text{C}\text{H}4}}\right)\)

0.655 ± 0.175

0.689 ± 0.175

0.035 ± 0.044

0.933–0.963

0.950

Substantial